神经干细胞和祖细胞研究

神经干细胞具有增殖、自我更新和产生大量可分化为神经元、星形胶质细胞和少突胶质细胞的细胞的能力。 查看更多 They have been identified in nearly all regions of the developing mouse, rat and human central nervous system (CNS) and in specialized neurogenic regions of the mature CNS. Recently, malignant multipotent neural stem cell-like cells, or brain tumor stem cells (BTSCs) , have been isolated from different grades (low and high) and types of brain cancers. They have the same characteristics as neural stem cells. Neural stem and progenitor cells can either be cultured as free-floating aggregates (neurospheres) or as an adherent monolayer of cells. Our media support both techniques and are available in formulations for human or mouse and rat neural stem cells isolated from normal and tumor tissues. These standardized media enable efficient expansion of neural stem cells in culture, while maintaining self-renewal, proliferation and differentiation potential.