切换导航
  • 比较产品
我的购物车

重组人FGF-7 （KGF）

成纤维细胞生长因子7
率先评论此产品
添加并比较

产品号 #（选择产品）

产品号 #78046_C

成纤维细胞生长因子7

main product photo
总览
实验数据
产品说明书及文档
应用领域
相关材料与文献
相关产品

总览

成纤维细胞生长因子 7 (FGF-7) 是 FGF 家族的成员，其作用机制主要通过主要由上皮细胞表达的 FGF 受体亚型发挥作用 (Finch & Rubin)。FGF-7 似乎特异性地作用于上皮细胞，并刺激这些细胞的增殖、迁移和分化，并且还参与体内和体外上皮的保护和修复 (Finch & Rubin; Werner)。相反，FGF-7 仅由间充质细胞产生，并作为间充质-上皮通讯的旁分泌介质发挥作用 (Rubin et al.)。FGF-7 还被证实可以补充生物工程皮肤的多种伤口愈合特性 (Erdag et al.)，并诱导人角质形成细胞的自噬 (Belleudi et al.)。此外，FGF-7 在多能干细胞分化为内胚层胰腺样胰岛素分泌细胞和胸腺上皮细胞中发挥作用（Inami et al.; Niu et al.）。

亚型
细胞因子，生长因子
 
细胞类型
内胚层，PSC衍生，造血干/祖细胞，角质形成细胞，乳腺细胞，间充质干/祖细胞，神经细胞，PSC衍生，神经干/祖细胞，多能干细胞，前列腺细胞
 
种属
人
 
研究领域
上皮细胞研究，神经科学，干细胞生物学
 
纯度
≥ 97 %
 

查看更多 显示更少

Data Figures

(A) The biological activity of Human Recombinant FGF-7 (KGF) was tested by its ability to promote the proliferation of 4MBr-5 cells. Cell proliferation was measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum. The EC50 in the example above is less than 2 ng/mL. (B) 2 μg of Human Recombinant FGF-7 (KGF) was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining. Human Recombinant FGF-7 (KGF) has a predicted molecular mass of 19 kDa.

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet
Product Name
Human Recombinant FGF-7 (KGF)
Catalog #
78046.2, 78046, 78046.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Human Recombinant FGF-7 (KGF)
Catalog #
78046.2, 78046, 78046.1
Lot #
All
Language
English

Resources and Publications

Educational Materials (1)

Cytokines, Chemokines and Growth Factors
Brochure
Cytokines, Chemokines and Growth Factors

更多信息

更多信息
Species Human
Purity ≥ 97%
STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.
版权 © 2025 STEMCELL Technologies 技术有限公司。保留所有权利。