产品号 #76010_C
定制设计的CRISPR RNA用于CRISPR- cas9基因组编辑中引导RNA的生成
Products for Your Protocol
To see all required products for your protocol, please consult the Protocols and Documentation.
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ArciTect™ Cas9 NucleaseCas9 nuclease for the generation of double-strand breaks in CRISPR-Cas9 genome editing
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ArciTect™ tracrRNA KitTrans-activating crRNA for guide RNA generation in CRISPR-Cas9 genome editing
概述
architect™crRNA是一种定制的CRISPR RNA (crRNA)，是制作CRISPR- cas9基因组编辑向导RNA （gRNA）模板所需的两种合成RNA成分之一。ArciTect™crRNA包含一个用户指定的19 - 21个碱基序列，与要切割的基因组位置互补，以及一个与ArciTect™tracrRNA（目录#76016）互补的连接子序列，允许快速有效的gRNA双工形成。architect™crRNA应设计成直接位于原间隔邻近基序（protospacer邻基序，PAM）位点（NGG）的上游。它在前两个5‘和3’末端残基上含有2'- o -甲基和磷硫酸修饰，以获得最佳的稳定性和编辑效率
Cell Type
Pluripotent Stem Cells
Species
Human
Application
Genome Editing
Area of Interest
Stem Cell Biology
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Resources and Publications
Educational Materials (9)
更多信息
| Species | Human |
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Legal Statement: The purchase of the ArciTect™ products conveys to the purchaser the limited, non-transferable right to use, in accordance with all applicable laws and regulations, the ArciTect™ products and any related material solely for research purposes only, not for any clinical, human, agricultural, veterinary, livestock, or commercial purpose, with no warranty (express or implied) from the owners or assignees of the Patents or STEMCELL Technologies each of whom expressly disclaim any warranty regarding results obtained through the use of the ArciTect™ products, and without any exception the owners or assignees of the Patents or STEMCELL Technologies, or as applicable a director, trustee, officer, employee, agent, faculty, official investigator or student thereof, will not suffer or be exposed to any liability, damages, loss, or expense of any kind whatsoever arising from or related to the use of the ArciTect™ products by a purchaser of same. Distribution of ArciTect™ products by STEMCELL Technologies is covered under at least US 8,697,359, US 8,771,945, US 8,795,965, US 8,865,406, US 8,871,445, US 8,889,356, US 8,889,418, US 8,895,308, US 8,906,616 and foreign equivalents (“Patents”). PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
