产品号 #76010_C
定制设计的 CRISPR RNA，用于 CRISPR-Cas9 基因组编辑中的guide RNA 生成
总览
ArciTect™ crRNA 是一种定制的 CRISPR RNA (crRNA)，是制作用于 CRISPR-Cas9 基因组编辑的guide RNA (gRNA) 模板所需的两种合成 RNA 组分之一。ArciTect™ crRNA 包含一个由用户指定的 19 至 21 个碱基的序列，该序列与目标基因组位点互补，并带有一个与 ArciTect™ tracrRNA（产品号 #76016）互补的连接序列，可快速高效地形成 gRNA 双链结构。ArciTect™ crRNA 的设计应位于原型间隔区邻近基序 (PAM) 位点 (NGG) 位点的正上游。其 5' 和 3' 末端的前两个残基含有 2'-O-甲基和硫代磷酸酯修饰，以提升其稳定性和编辑效率。
细胞类型
多能干细胞
种属
人
应用
基因组编辑
研究领域
干细胞生物学
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Resources and Publications
Educational Materials (9)
更多信息
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Legal Statement: The purchase of the ArciTect™ products conveys to the purchaser the limited, non-transferable right to use, in accordance with all applicable laws and regulations, the ArciTect™ products and any related material solely for research purposes only, not for any clinical, human, agricultural, veterinary, livestock, or commercial purpose, with no warranty (express or implied) from the owners or assignees of the Patents or STEMCELL Technologies each of whom expressly disclaim any warranty regarding results obtained through the use of the ArciTect™ products, and without any exception the owners or assignees of the Patents or STEMCELL Technologies, or as applicable a director, trustee, officer, employee, agent, faculty, official investigator or student thereof, will not suffer or be exposed to any liability, damages, loss, or expense of any kind whatsoever arising from or related to the use of the ArciTect™ products by a purchaser of same. Distribution of ArciTect™ products by STEMCELL Technologies is covered under at least US 8,697,359, US 8,771,945, US 8,795,965, US 8,865,406, US 8,871,445, US 8,889,356, US 8,889,418, US 8,895,308, US 8,906,616 and foreign equivalents (“Patents”). PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
