Human iPSC-Derived Mesenchymal Progenitor Cells
Frozen human mesenchymal progenitor cells differentiated from human induced pluripotent stem cell line, SCTi003-A
Start your mesenchymal cultures confidently with high-quality, ready-to-use Human iPSC-Derived Mesenchymal Progenitor Cells (MPCs). These cryopreserved multipotent progenitor cells are differentiated from the human induced pluripotent stem cell (iPSC) control line, SCTi003-A, derived from healthy female donor peripheral blood mononuclear cells (PBMCs). Ready to use directly from thawing, MPCs are multipotent and can be reliably cultured and differentiated using our MesenCult™ media line. The MPCs readily differentiate into cells of the mesenchymal lineage, such as adipocytes (MesenCult™ Adipogenic Differentiation Kit [Human]), osteoblasts (MesenCult™ Osteogenic Differentiation Kit [Human]), and chondrocytes (MesenCult™ Chondrogenic Differentiation Kit [Human]).
To ensure high quality, Human iPSC-Derived MPCs were differentiated from SCTi003-A cells using STEMdiff™ Mesenchymal Progenitor Kit. The resultant MPCs express high levels of mesenchymal cell markers, such as CD73, CD90, and CD105, and are capable of long-term expansion when cultured with MesenCult™-ACF Plus Medium (also included in MesenCult™-ACF Plus Culture Kit). The MPCs may also be cryopreserved for storage using MesenCult™-ACF Freezing Medium, allowing for flexibility in your workflow. MPCs, as well as the adipogenic, osteogenic, and chondrogenic cells generated from them, can be used for studying regenerative medicine development, drug discovery, and disease modeling.
This research-use-only (RUO) product has been approved for both academic and commercial use. Blood samples are ethically sourced using Institutional Review Board (IRB) or other regulatory authority-approved consent forms and protocols. For donor details and cell quality characterization of the source cell banks, refer to the data figures on this page. For additional details, refer to Frequently Asked Questions about iPSC lines.
To ensure high quality, Human iPSC-Derived MPCs were differentiated from SCTi003-A cells using STEMdiff™ Mesenchymal Progenitor Kit. The resultant MPCs express high levels of mesenchymal cell markers, such as CD73, CD90, and CD105, and are capable of long-term expansion when cultured with MesenCult™-ACF Plus Medium (also included in MesenCult™-ACF Plus Culture Kit). The MPCs may also be cryopreserved for storage using MesenCult™-ACF Freezing Medium, allowing for flexibility in your workflow. MPCs, as well as the adipogenic, osteogenic, and chondrogenic cells generated from them, can be used for studying regenerative medicine development, drug discovery, and disease modeling.
This research-use-only (RUO) product has been approved for both academic and commercial use. Blood samples are ethically sourced using Institutional Review Board (IRB) or other regulatory authority-approved consent forms and protocols. For donor details and cell quality characterization of the source cell banks, refer to the data figures on this page. For additional details, refer to Frequently Asked Questions about iPSC lines.
Data Figures
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Resources and Publications
Educational Materials (1)
Legal Statement: These iPSCs and their modifications (including but not limited to derivatives or differentiated progeny) shall not be used or administered in (1) human subjects for human clinical use; (2) animals for veterinary use for therapeutic, diagnostic, or prophylactic purposes or (3) any subject in relation to clinical applications, cell therapy, transplantation, and/or regenerative medicines, without limiting the generality of the foregoing. These iPSCs and their modifications (including but not limited to derivatives or differentiated progeny) may not be used for monetization or commercialization purposes, including without limitation, used to, or with the goal to, perform services or supply products or rights, including in the manufacture of cellular therapies or other therapeutics, for monetary gain or the generation of royalties, revenues, sales or other valuable consideration. For clarity, these iPSCs and their modifications (including but not limited to derivatives or differentiated progeny) may not be used for screening compounds, antibodies, proteins or peptides, except for the purposes of target discovery, target validation, or assay development, provided such activities and the results of such activities are not further used for monetization or commercialization purposes. It may be possible to obtain a further license for the prohibited uses referred to in this Limited Use License. Please contact iPSCrequests@stemcell.com for more details. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.
