切换导航
  • 比较产品
我的购物车

重组小鼠IL-1 α

白介素1α
率先评论此产品
添加并比较

产品号 #（选择产品）

产品号 #78129_C

白介素1α

main product photo
总览
实验数据
产品说明书及文档
应用领域
相关材料与文献
相关产品

总览

白介素1α (IL-1α)是IL-1家族的成员，是一种双重功能的细胞因子。未加工的前体和加工过的IL-1α蛋白都可通过IL-1受体1 （IL-1R1）进行信号传导。多种细胞类型，包括角化细胞、胸腺上皮、肝细胞、内皮细胞、成纤维细胞和粘膜上皮细胞，细胞内IL-1α前体蛋白水平较高，此外，在单核细胞和B淋巴细胞表面也有表达（Netea等人）。IL-1α在坏死过程中，可将浸润细胞募集到损伤部位，并在无菌炎症过程中发挥重要作用(Rider等人；Cohen等人)。在缺氧状态下，IL-1α有助于血管生成（Carmi等人）。缺血性脑损伤后，小胶质细胞产生IL-1α，导致炎症反应的发生（Luheshi 等人）。

亚型
细胞因子
 
别名
BAF；B细胞激活因子；表皮细胞来源的胸腺细胞激活因子；ETAF；FAF；成纤维细胞激活因子；IL-1F1；LAF；LEM；白细胞内源性介质；淋巴细胞激活因子；MCF；单核细胞因子
 
细胞类型
血管生成细胞，B 细胞，内皮细胞，上皮细胞，巨噬细胞，单核细胞，神经干/祖细胞
 
种属
小鼠
 
研究领域
血管生成细胞研究，内皮细胞研究，上皮细胞研究，免疫
 
分子量
18.1 千道尔顿
 
纯度
≥ 95 %
 

查看更多 显示更少

Data Figures

(A) The biological activity of Mouse Recombinant IL-1 alpha was tested by its ability to promote the proliferation of D10.G4.1 cells. Cell proliferation was measured after 72 hours of culture using a fluorometric assay method. The EC50 is defined as the effective concentration of the cytokine at which cell proliferation is at 50% of maximum. The EC50 in the example above is 0.00581 ng/mL. (B) 1 μg of Mouse Recombinant IL-1 alpha was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining.

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet
Product Name
Mouse Recombinant IL-1 alpha
Catalog #
78129.1, 78129.2
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Mouse Recombinant IL-1 alpha
Catalog #
78129.1, 78129.2
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Research Area
Workflow Stages

更多信息

更多信息
Molecular Weight 18.1 kDa
Species Mouse
Alternative Names BAF, B-cell-activating factor, Epidermal cell-derived thymocyte-activating factor, ETAF, FAF, Fibroblast-activating factor, IL-1F1, LAF, LEM, Leukocyte endogenous mediator, Lymphocyte-activating factor, MCF, Mononuclear cell factor
Purity ≥ 95%
STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.
版权 © 2025 STEMCELL Technologies 技术有限公司。保留所有权利。