产品号 #60144_C
Rabbit polyclonal antibody against human, mouse SHIP
概述
The SH2-containing inositol phosphatase (SHIP, also called SHIP1) is a 145 kDa hematopoietic-restricted protein that becomes tyrosine-phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation. SHIP also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway. This antibody reacts with mouse and human full-length 145 kDa SHIP protein.
Subtype
Primary Antibodies
Target Antigen
SHIP
Alternative Names
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; p150Ship; SHIP1; SHIP-1; s-SHIP; SIP-145
Reactive Species
Human, Mouse
Conjugation
Unconjugated
Host Species
Rabbit
Cell Type
Granulocytes and Subsets, Lymphocytes, Myeloid Cells
Species
Human, Mouse
Application
Immunoblotting, Immunoprecipitation
Area of Interest
Immunology
Clone
Not applicable
Gene ID
3635 (human), 16331 (mouse)
Isotype
Not applicable
Data Figures
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Anti-SHIP (C-Terminus) Antibody, Polyclonal Catalog #
60144 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-SHIP (C-Terminus) Antibody, Polyclonal Catalog #
60144 Lot #
All Language
English Resources and Publications
Educational Materials (2)
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