抗SHIP抗体,多克隆

兔多克隆抗体,抗小鼠SHIP

产品号 #(选择产品)

产品号 #60141_C

兔多克隆抗体,抗小鼠SHIP

总览

含有SH2结构域的肌醇磷酸酶(SHIP,也称为SHIP1)是一种分子量为145 kDa的造血限制性蛋白。在细胞因子、生长因子、趋化因子和免疫受体的刺激下,该蛋白会发生酪氨酸磷酸化并与适配蛋白Shc结合。SHIP通过水解磷脂酰肌醇3激酶(PI3K)产生的关键第二信使PI-3,4,5-P3(PIP3),生成PI-3,4-P2,因此是PI3K途径的重要负调控因子。该抗体可识别小鼠全长SHIP蛋白(145 kDa)以及C端截短的135 kDa、125 kDa和110 kDa形式。

亚型
一抗
 
靶抗原
SHIP
 
别名
磷脂酰肌醇3,4,5-三磷酸5-磷酸酶1;p150Ship; SHIP1;SHIP-1;s-SHIP;SIP-145
 
活性物种
人,小鼠
 
偶联
未偶联的
 
宿主物种

 
细胞类型
粒细胞及其亚群,淋巴细胞,髓系细胞
 
种属
人,小鼠
 
应用
免疫印迹,免疫沉淀
 
研究领域
免疫
 
克隆
Not applicable
 
基因编号
16331
 
同种型
Not applicable
 

Data Figures

Western blot analysis of mouse bone marrow derived mast cells (BMMCs) from normal (+/+) and SHIP knockout (-/-) mice with Anti-SHIP Antibody, Polyclonal (1:4000 dilution). SHIP has a predicted molecular mass of 145 kDa.

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
60141
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60141
Lot #
All
Language
English

Resources and Publications

Educational Materials (2)

更多信息

更多信息
Species Human, Mouse
Clone Not applicable
Gene Id 16331
Alternative Names Phosphatidylinositol 3, 4, 5-trisphosphate 5-phosphatase 1; p150Ship; SHIP1; SHIP-1; s-SHIP; SIP-145
Isotype Not applicable
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