产品号 #100-1636_C
Rat monoclonal antibody against mouse Ly-6C
概述
This monoclonal antibody (clone HK1.4) reacts with mouse lymphocyte antigen 6 family member C (Ly-6C), a 14 - 17 kDa glycosylphosphatidylinositol (GPI)-linked protein of the Ly6 family. Ly-6C is expressed on monocytes, macrophages, endothelial cells, granulocytes, and a subset of lymphocytes. Use this recombinant monoclonal antibody in applications requiring detection of Ly-6C, such as flow cytometry (FC).
It has been reported that Ly-6C is an indicator of memory CD8+ T cells. Ly-6C is regulated by interferon gamma and may play a role in the development and maturation of lymphocytes. Some variation of Ly-6C expression on CD4 and CD8 lymphocytes is found in different mouse strains. Mouse strains with the Ly-6.2 alloantigen have subsets of CD4 and CD8 cells that express Ly-6.2, whereas strains with the Ly-6.1 alloantigen possess only Ly-6.1+ CD8 subsets.
Subtype
Primary Antibodies
Target Antigen
Ly-6C
Alternative Names
Ly6C, Ly-6C1
Reactive Species
Mouse
Conjugation
APC, PE, PerCP-Cyanine5.5
Host Species
Rat
Cell Type
Endothelial Cells, Granulocytes and Subsets, Lymphocytes, Macrophages, Monocytes
Species
Mouse
Application
Flow Cytometry
Area of Interest
Immunology
Clone
HK1.4
Gene ID
17067
Isotype
IgG2c, kappa
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Anti-Mouse Ly-6C Antibody, Clone HK1.4, PerCP-Cy5.5 Catalog #
100-1638 Lot #
All Language
English Document Type
Product Information Sheet Product Name
Anti-Mouse Ly-6C Antibody, Clone HK1.4, PE Catalog #
100-1636 Lot #
All Language
English Document Type
Product Information Sheet Product Name
Anti-Mouse Ly-6C Antibody, Clone HK1.4, APC Catalog #
100-1637 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Mouse Ly-6C Antibody, Clone HK1.4, PerCP-Cy5.5 Catalog #
100-1638 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Mouse Ly-6C Antibody, Clone HK1.4, PE Catalog #
100-1636 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Mouse Ly-6C Antibody, Clone HK1.4, APC Catalog #
100-1637 Lot #
All Language
English Resources and Publications
Educational Materials (2)
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