产品号 #100-1615_C
Hamster (Armenian) monoclonal antibody against mouse CD69
概述
This monoclonal antibody (clone H1.2F3) reacts with mouse cluster of differentiation 69 (CD69), a type II transmembrane glycoprotein. CD69 is a 60 kDa disulfide bonded homodimer expressed on activated T cells, B cells, NK cells, neutrophils, and monocytes, where induction of CD69 rapidly occurs upon activation. CD69 is constitutively expressed on platelets and a subset of thymocytes. It functions as a co-stimulatory molecule that plays a role in activating and promoting the proliferation of T cells. Additionally, it can serve as an indicator for thymocytes engaged in T cell receptor (TCR)-mediated positive selection. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. It has also been documented that co-stimulation with the H1.2F3 antibody clone enhances the activation of T cells and macrophages. CD69 dysfunction is associated with diseases such as coccidioidomycosis and asthma. Use this recombinant monoclonal antibody in applications requiring detection of CD69, such as flow cytometry (FC).
Subtype
Primary Antibodies
Target Antigen
CD69
Alternative Names
AIM, CLEC2C, EA1, gp34/28, Leu23, MLR3, VEA, very early activation antigen
Reactive Species
Mouse
Conjugation
APC, FITC, PE, PE-Cyanine7
Host Species
Hamster
Cell Type
B Cells, Macrophages, Monocytes, NK Cells, T Cells
Species
Mouse
Application
Flow Cytometry
Area of Interest
Immunology
Clone
H1.2F3
Gene ID
12515
Isotype
Armenian hamster IgG
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Anti-Mouse CD69 Antibody, Clone H1.2F3, APC Catalog #
100-1618 Lot #
All Language
English Document Type
Product Information Sheet Product Name
Anti-Mouse CD69 Antibody, Clone H1.2F3, FITC Catalog #
100-1617 Lot #
All Language
English Document Type
Product Information Sheet Product Name
Anti-Mouse CD69 Antibody, Clone H1.2F3, PE Catalog #
100-1616 Lot #
All Language
English Document Type
Product Information Sheet Product Name
Anti-Mouse CD69 Antibody, Clone H1.2F3, PE-Cy7 Catalog #
100-1615 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Mouse CD69 Antibody, Clone H1.2F3, APC Catalog #
100-1618 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Mouse CD69 Antibody, Clone H1.2F3, FITC Catalog #
100-1617 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Mouse CD69 Antibody, Clone H1.2F3, PE Catalog #
100-1616 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Mouse CD69 Antibody, Clone H1.2F3, PE-Cy7 Catalog #
100-1615 Lot #
All Language
English Resources and Publications
Educational Materials (2)
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