Human iPSC-Derived Neural Progenitor Cells
Frozen human neural progenitor cells differentiated from the human induced pluripotent stem cell line, SCTi003-A
Start your neural workflow confidently with high-quality, ready-to-use human neural progenitor cells (NPCs). These specially cryopreserved central nervous system (CNS)-type progenitors are differentiated from the human induced pluripotent stem cell (iPSC) control line, SCTi003-A, which is derived from healthy female donor peripheral blood mononuclear cells (PBMCs). Ready to use directly from thawing, these human NPCs are multipotent and suitable for customized downstream differentiation to various CNS cell types, such as forebrain neurons, midbrain neurons, and astrocytes, using STEMdiff™ kits.
To ensure high-quality cells, these NPCs were differentiated from the robust, extensively tested SCTi003-A line using serum-free STEMdiff™ SMADi Neural Induction Kit. NPCs can be expanded using STEMdiff™ Neural Progenitor Medium, allowing for scale-up and reducing the cost of workflows that require large numbers of cells. Cryopreserve expanded NPCs using STEMdiff™ Neural Progenitor Freezing Medium for flexibility in your experimental schedule.
This research-use-only (RUO) product has been consented for both academic and commercial use. Blood samples are ethically sourced using Institutional Review Board (IRB) or other regulatory authority-approved consent forms and protocols. For donor details and cell quality characterization of the source cell banks, refer to the data figures on this page. SCTi003-A is derived from an αβ T cell and has undergone VDJ sequence rearrangement. It is karyotypically stable, demonstrates trilineage differentiation potential, expresses undifferentiated cell markers, and was reprogrammed using a non-integrating reprogramming technology. Registration with hPSCreg® ensures ethical and biological conformity based on community standards. For additional details, refer to the lot-specific Certificate of Analysis and Frequently Asked Questions about iPSC lines.
To ensure high-quality cells, these NPCs were differentiated from the robust, extensively tested SCTi003-A line using serum-free STEMdiff™ SMADi Neural Induction Kit. NPCs can be expanded using STEMdiff™ Neural Progenitor Medium, allowing for scale-up and reducing the cost of workflows that require large numbers of cells. Cryopreserve expanded NPCs using STEMdiff™ Neural Progenitor Freezing Medium for flexibility in your experimental schedule.
This research-use-only (RUO) product has been consented for both academic and commercial use. Blood samples are ethically sourced using Institutional Review Board (IRB) or other regulatory authority-approved consent forms and protocols. For donor details and cell quality characterization of the source cell banks, refer to the data figures on this page. SCTi003-A is derived from an αβ T cell and has undergone VDJ sequence rearrangement. It is karyotypically stable, demonstrates trilineage differentiation potential, expresses undifferentiated cell markers, and was reprogrammed using a non-integrating reprogramming technology. Registration with hPSCreg® ensures ethical and biological conformity based on community standards. For additional details, refer to the lot-specific Certificate of Analysis and Frequently Asked Questions about iPSC lines.
Data Figures
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Resources and Publications
Educational Materials (11)
Legal Statement: These iPSCs and their modifications (including but not limited to derivatives or differentiated progeny) shall not be used or administered in (1) human subjects for human clinical use; (2) animals for veterinary use for therapeutic, diagnostic, or prophylactic purposes or (3) any subject in relation to clinical applications, cell therapy, transplantation, and/or regenerative medicines, without limiting the generality of the foregoing. These iPSCs and their modifications (including but not limited to derivatives or differentiated progeny) may not be used for monetization or commercialization purposes, including without limitation, used to, or with the goal to, perform services or supply products or rights, including in the manufacture of cellular therapies or other therapeutics, for monetary gain or the generation of royalties, revenues, sales or other valuable consideration. For clarity, these iPSCs and their modifications (including but not limited to derivatives or differentiated progeny) may not be used for screening compounds, antibodies, proteins or peptides, except for the purposes of target discovery, target validation, or assay development, provided such activities and the results of such activities are not further used for monetization or commercialization purposes. It may be possible to obtain a further license for the prohibited uses referred to in this Limited Use License. Please contact iPSCrequests@stemcell.com for more details. UNLESS OTHERWISE STATED, PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES. FOR PRODUCT-SPECIFIC COMPLIANCE AND INTENDED USE INFORMATION, REFER TO THE PRODUCT INFORMATION SHEET. GENERAL INFORMATION ON QUALITY AT STEMCELL MAY BE FOUND AT WWW.STEMCELL.COM/COMPLIANCE.
