产品号 #60151_C
Rat monoclonal IgG2b antibody against mouse CD54
概述
The YN1/1.7.4 antibody reacts with CD54, a 90 - 110 kDa type I transmembrane glycoprotein that is a member of the immunoglobulin (Ig) superfamily. CD54 consists of five Ig-like C2 type domains and has two isoforms generated from alternative splicing. As an important intercellular adhesion molecule, CD54 is involved in inflammatory reactions, antigen-specific immune responses, lymphocyte trafficking, and T cell signal transduction events. CD54 mediates important cell-cell interactions and adhesion reactions by binding to its major ligands, LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 may also act as a receptor for rhinoviruses and some coxsackieviruses. CD54 is expressed on lymphocytes, monocytes, macrophages, dendritic cells, endothelial cells, and high endothelial venules. Expression of CD54 is upregulated on activated lymphocytes and also, following stimulation with inflammatory mediators such as cytokines, LPS, and IFN-γ.
Subtype
Primary Antibodies
Target Antigen
CD54 (ICAM-1)
Alternative Names
BB2, Cell surface glycoprotein P3.58, Human rhinovirus receptor, Intercellular adhesion molecule 1, Ly-47, MALA2, MyD10
Reactive Species
Mouse
Conjugation
Unconjugated
Host Species
Rat
Cell Type
Endothelial Cells
Species
Mouse
Application
Cell Isolation, Flow Cytometry, Immunoblotting, Immunoprecipitation
Area of Interest
Immunology
Clone
YN1/1.7.4
Gene ID
15894
Isotype
IgG2b, kappa
Data Figures
Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD54 (ICAM-1) Antibody, Clone YN/1.7.4, followed by a mouse anti-rat IgG2b antibody, FITC (filled histogram) or Rat IgG2b, kappa Isotype Control Antibody, Clone RTK4530 (Catalog #60077), followed by a mouse anti-rat IgG2b antibody, FITC (solid line histogram).
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Anti-Mouse CD54 (ICAM-1) Antibody, Clone YN1/1.7.4 Catalog #
60151.1, 60151 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Mouse CD54 (ICAM-1) Antibody, Clone YN1/1.7.4 Catalog #
60151.1, 60151 Lot #
All Language
English Resources and Publications
Educational Materials (2)
Request Pricing
Thank you for your interest in IntestiCult™ Organoid Growth Medium (Human). Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n):
Estimated delivery time for your area
Product sample or exclusive offer
In-lab demonstration
By submitting this form, you are providing your consent to STEMCELL Technologies Canada Inc. and its subsidiaries and affiliates (“STEMCELL”) to collect and use your information, and send you newsletters and emails in accordance with our
privacy policy. Please contact us with any questions that you may have. You can unsubscribe or change your email preferences at any time.
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
欢迎您关注STEMCELL Technologies的微信公众平台
扫描二维码或搜索微信号STEMCELLTech，即可关注我们的微信平台，第一时间接收丰富的技术资源和最新的活动信息。
如您有任何问题，欢迎发消息给STEMCELLTech微信公众平台，或与我们通过电话/邮件联系：400 885 9050 INFO.CN@STEMCELL.COM。