产品号 #60126_C
Mouse monoclonal IgG1 antibody against human CD33
概述
The P67.6 antibody reacts with CD33 (Siglec-3), a 67 kDa type 1 transmembrane sialoadhesin protein of the immunoglobulin superfamily. CD33 is expressed on committed myeloid progenitor cells, monocytes, granulocytes, dendritic cells, mast cells, resident macrophages, subsets of B cells, and activated T and NK cells. CD33 is a major marker used to differentiate myeloid from lymphoid or erythroid leukemias. In peripheral blood, it is expressed at high levels on monocytes and at lower levels on granulocytes. CD33 functions as a sialic acid-dependent cell adhesion molecule and mediates protein-glycan and protein-protein interactions between cells. It also has a putative role as an inhibitory receptor during the immune response.
Subtype
Primary Antibodies
Target Antigen
CD33
Reactive Species
Human
Conjugation
PE
Host Species
Mouse
Cell Type
Granulocytes and Subsets, Myeloid Cells
Species
Human
Application
Cell Isolation, Flow Cytometry
Area of Interest
Immunology
Clone
P67.6
Gene ID
945
Data Figures
Figure 1. Data for PE-Conjugated
Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD33 Antibody, Clone P67.6, PE (filled histogram) or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, PE (Catalog #60070PE; solid line histogram).
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Anti-Human CD33 Antibody, Clone P67.6, PE Catalog #
60126PE, 60126PE.1 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Human CD33 Antibody, Clone P67.6, PE Catalog #
60126PE, 60126PE.1 Lot #
All Language
English Resources and Publications
Educational Materials (2)
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