抗乙酰化α-微管蛋白(乙酰基K40)抗体,克隆TEU318

抗人、小鼠、大鼠乙酰化α-微管蛋白(乙酰化K40)的小鼠单克隆IgG1抗体

产品号 #(选择产品)

产品号 #100-0753_C

抗人、小鼠、大鼠乙酰化α-微管蛋白(乙酰化K40)的小鼠单克隆IgG1抗体

总览

TEU318抗体可与乙酰化形式的 α-微管蛋白(一种 55 kDa 的蛋白质)发生反应。在真核细胞中,α-微管蛋白和β-微管蛋白结合形成异二聚体,是微管的关键组成部分。这些微管是真核细胞的丝状圆柱状细胞骨架结构支撑元件。这些微管的稳定性可以通过翻译后修饰改变,例如 α-微管蛋白的乙酰化。乙酰基转移酶 α-Tat1 (Mec-17) 可以将乙酰基添加到 α-微管蛋白的 Lys40 位点,这种翻译后修饰有助于稳定微管的整体结构。研究表明,乙酰化微管蛋白可能在微管结构和功能的分化中发挥关键作用。

靶抗原
Acetylated Alpha-Tubulin
 
别名
α‑微管蛋白(K40 乙酰化)
 
活性物种
人,小鼠,其它细胞系,大鼠
 
偶联
未偶联的
 
宿主物种
小鼠
 
细胞类型
气道细胞,上皮细胞
 
应用
免疫细胞化学,免疫荧光,Western印迹
 
研究领域
疾病建模,上皮细胞研究,呼吸系统研究
 
克隆
TEU318
 
基因编号
7846
 
同种型
IgG1
 

Data Figures

Confocal image of immunostained human bronchial epithelial cells.

Figure 1. Anti-Acetylated Alpha-Tubulin (Acetyl K40) Antibody, Clone TEU319 is Suitable for Staining Human Bronchial Epithelial Cells

HBECs cultured in PneumaCult™-ALI Medium were fixed, permeabilized, and labeled with Anti-Acetylated Alpha-Tubulin Antibody (Acetyl K40), Clone TEU318, followed by goat anti-mouse IgG1, Alexa Fluor® 488. Nuclei were counter-stained with DAPI (blue). Inset shows cells labeled with a mouse IgG1, kappa isotype control antibody, followed by goat anti-mouse IgG1, Alexa Fluor® 488 (with DAPI staining).

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-0753
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-0753
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

更多信息

更多信息
Clone TEU318
Gene Id 7846
Alternative Names α-tubulin (acetyl K40)
Isotype IgG1
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