产品号 #100-0753_C
抗人、小鼠、大鼠乙酰化α-微管蛋白(乙酰化K40)的小鼠单克隆IgG1抗体
TEU318抗体可与乙酰化形式的 α-微管蛋白(一种 55 kDa 的蛋白质)发生反应。在真核细胞中,α-微管蛋白和β-微管蛋白结合形成异二聚体,是微管的关键组成部分。这些微管是真核细胞的丝状圆柱状细胞骨架结构支撑元件。这些微管的稳定性可以通过翻译后修饰改变,例如 α-微管蛋白的乙酰化。乙酰基转移酶 α-Tat1 (Mec-17) 可以将乙酰基添加到 α-微管蛋白的 Lys40 位点,这种翻译后修饰有助于稳定微管的整体结构。研究表明,乙酰化微管蛋白可能在微管结构和功能的分化中发挥关键作用。
靶抗原
Acetylated Alpha-Tubulin
别名
α‑微管蛋白(K40 乙酰化)
活性物种
人,小鼠,其它细胞系,大鼠
偶联
未偶联的
宿主物种
小鼠
细胞类型
气道细胞,上皮细胞
应用
免疫细胞化学,免疫荧光,Western印迹
研究领域
疾病建模,上皮细胞研究,呼吸系统研究
克隆
TEU318
基因编号
7846
同种型
IgG1
Figure 1. Anti-Acetylated Alpha-Tubulin (Acetyl K40) Antibody, Clone TEU319 is Suitable for Staining Human Bronchial Epithelial Cells
HBECs cultured in PneumaCult™-ALI Medium were fixed, permeabilized, and labeled with Anti-Acetylated Alpha-Tubulin Antibody (Acetyl K40), Clone TEU318, followed by goat anti-mouse IgG1, Alexa Fluor® 488. Nuclei were counter-stained with DAPI (blue). Inset shows cells labeled with a mouse IgG1, kappa isotype control antibody, followed by goat anti-mouse IgG1, Alexa Fluor® 488 (with DAPI staining).
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Clone | TEU318 |
---|---|
Gene Id | 7846 |
Alternative Names | α-tubulin (acetyl K40) |
Isotype | IgG1 |
无血清和无bpe培养基用于原代人气道上皮细胞的扩增
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