产品号 #73912_C
MEK/ERK通路抑制剂；抑制VEGFR2，FGFR1和PDGFRB
总览
SU5402是血管内皮生长因子受体2（VEGFR-2）、成纤维细胞生长因子受体1（FGFR-1）和血小板衍生生长因子受体β (PDGFRB) 的有效选择性抑制剂，IC₅₀分别为0.02、0.03和0.51µM （Sun et al.）。
细胞类型
癌细胞及细胞系，杂交瘤细胞，多能干细胞
种属
人，小鼠，非人灵长类，其它细胞系，大鼠
应用
培养
研究领域
抗体制备，癌症，疾病建模，杂交瘤制备，免疫，干细胞生物学
CAS 编号
215543-92-3
化学式
C₁₇H₁₆N₂O₃
纯度
≥ 95 %
通路
MEK/ERK
靶点
FGFR，PDGFR
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Resources and Publications
Educational Materials (4)
更多信息
| Species | Human, Mouse, Non-Human Primate, Other, Rat |
|---|---|
| Cas Number | 215543-92-3 |
| Chemical Formula | C₁₇H₁₆N₂O₃ |
| Purity | ≥ 95% |
| Target | FGFR, PDGFR |
| Pathway | MEK/ERK |
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PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
