先天淋巴细胞 (ILC) 是近期发现的一个细胞家族,其特征是能够产生 T 辅助细胞亚群相关的细胞因子,并且缺乏重排的抗原特异性受体。
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New studies have found that ILCs are implicated in immunity and tissue remodelling.1 Based on their cytokine production and transcription factor expression, ILCs have been categorized into three groups: ILC1s, ILC2s and ILC3s. ILCs are present in several tissues including lung, intestines, tonsils, skin and peripheral blood.1,2
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References
1. Artis D & Spits H. (2015) Nature 517(7534): 293–301.
2. Spits H & Cupedo T. (2012) Annu Rev Immunol 30(1): 647–675.
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