产品号 #100-1333_C
Fetuin B, His tag
概述
Fetuin B is thought to have functions in female fertility, metabolism, and liver disease. A protease inhibitor belonging to the fetuin family of proteins, within the cystatin superfamily, fetuin b’s structure includes two cystatin domains (CY1 and CY2) connected by a linker, with a CPDCP-trunk and a C-terminal region (CTR) (Cuppari et al.). This plasma protein originates in the liver (Denecke et al.) and acts to inhibit the activity of ovastacin, a metalloprotease that causes the zona pellucida to harden, leading to female infertility (Karmilin et al.). Fetuin B has also been reported to increase apoptosis, and inhibit migration and invasion of prostate cancer cells, in in vitro and in vivo settings (Zhan et al.). Elevated serum fetuin B has been linked to non-alcoholic fatty liver disease (NAFLD) (Zhu et al.). This protein contains a His-residue tag at the carboxyl end of the polypeptide chain. For consistency and reproducibility across your applications, apolipoprotein H from STEMCELL comes lyophilized with ≥ 92% purity, and is verified by LAL analysis to ensure endotoxin levels are ≤ 1.0 EU/μg protein.
Subtype
Cytokines
Alternative Names
16G2, Gugu, IRL685
Species
Human
Area of Interest
Metabolism
Purity
≥ 92%
Data Figures
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Human Recombinant Fetuin B Catalog #
100-1333 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Human Recombinant Fetuin B Catalog #
100-1333 Lot #
All Language
English Request Pricing
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