产品号 #100-1323_C
Fetuin A, His tag
概述
Mediate calcium phosphate clearance and prevent ectopic calcification with fetuin A, a plasma glycoprotein that forms soluble complexes with calcium and phosphate (Heiss et al.; Price & Lin). Belonging to the cystatin superfamily of cysteine protease inhibitors (Brown and Dziegielewska), fetuin A has also been shown to play a role in lipid transport, acting as a carrier (Kumbla et al.). In cell-based assays, it has been suggested that fetuin A protects against lethal systemic infection through the inhibition of high mobility group box 1 (HMGB1) protein accumulation and release (Li et al.). Fetuin A acts as a natural antagonist against specific TGF-β and BMP signaling proteins, blocking osteogenic differentiation of rat bone marrow cells (Demetriou et al.). This protein contains a His-residue tag at the carboxyl end of the polypeptide chain. For consistency and reproducibility across your applications, fetuin A from STEMCELL comes lyophilized with ≥ 94% purity, and endotoxin levels are verified to be ≤ 1.0 EU/μg protein.
Subtype
Cytokines
Alternative Names
A2HS, AHS, AHSG, FETUA, HSGA
Species
Human
Area of Interest
Metabolism
Purity
≥ 94%
Data Figures
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Human Recombinant Fetuin A Catalog #
100-1323 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Human Recombinant Fetuin A Catalog #
100-1323 Lot #
All Language
English Request Pricing
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