产品号 #100-1297_C
C-Reactive Protein
概述
A member of the pentraxin family of proteins, C-reactive protein (CRP) plays important roles in host defenses, including regulating complement activation in vivo (Sjoberg et al.), decreasing nitric oxide production, and inhibiting angiogenesis in vitro (Verma et al., 2002). At specific concentrations, CRP directly inhibits endothelial progenitor cell (EPC) differentiation, survival, and function, and is thus implicated in the development of cardiovascular diseases (Verma et al., 2004). CRP is primarily synthesized by liver hepatocytes, but also by other immune cells, such as macrophages and lymphocytes (Sproston & Ashworth). The expression of this acute-phase protein is induced by IL-6 and IL-1 secretion of macrophages and T-cells during inflammation. For consistency and reproducibility across your applications, C-reactive protein from STEMCELL comes lyophilized with ≥ 87% purity, and endotoxin levels are verified to be ≤ 1.0 EU/μg protein.
Subtype
Cytokines
Alternative Names
PTX1
Species
Human
Area of Interest
Metabolism
Purity
≥ 87%
Data Figures
Human Recombinant C-Reactive Protein was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining. Human Recombinant C-Reactive Protein has a predicted molecular mass of 23 kDa but an apparent molecular mass of 26 kDa due to glycosylation.
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Human Recombinant C-Reactive Protein Catalog #
100-1297 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Human Recombinant C-Reactive Protein Catalog #
100-1297 Lot #
All Language
English Request Pricing
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