产品号 #100-1322_C
Apolipoprotein A-I, His tag
概述
A member of the apolipoprotein family, Apolipoprotein A-I (apo A-I) is a major glycoprotein component of high density lipoprotein (HDL) particles (Frank & Marcel) which facilitate the reverse transport of cholesterol from peripheral tissues to the liver. Apo A-I binds to the scavenger receptor SR-A1, allowing HDL particles to interact with cells in peripheral tissues (Neyen et al.), and is involved in the esterification of cholesterol, acting as a cofactor for lecithin cholesterol acyltransferase (LCAT; Frohlich). Apo A-I has been shown to bind to the scavenger receptor SR-B1 (Williams et al.) and the beta chain of ATP synthase (Martinez et al.) on hepatocytes, highlighting its importance in HDL endocytosis. Mutations in the APOA1 encoding gene may result in dysregulated HDL levels, leading to an increased risk of amyloidosis and ischemic heart disease (Haase et al.; Obici et al.). This protein product contains a His-residue tag at the amino end of the polypeptide chain. This protein product contains a His-residue tag at the amino end of the polypeptide chain. For consistency and reproducibility across your applications, sclerostin from STEMCELL comes lyophilized with ≥ 92% purity.
Subtype
Cytokines
Alternative Names
Apolipoprotein A1
Species
Human
Area of Interest
Metabolism
Purity
≥ 92%
Data Figures
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Human Recombinant Apolipoprotein A-I Catalog #
100-1322 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Human Recombinant Apolipoprotein A-I Catalog #
100-1322 Lot #
All Language
English Request Pricing
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