Collagenase Type IV

For digestion of native collagen fibrils

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  • Maintain receptor integrity with a collagenase preparation low in tryptic activity

  • Dissociate pancreatic islet cells effectively

  • Digest native collagen fibrils in connective tissues with Collagenase Type IV, sourced from Clostridium histolyticum. Collagenase preparations typically contain the activity of several proteases, including collagenase, caseinase, clostripain, and trypsin (Kessler & Yaron). Frequently used to dissociate pancreatic islets (Taguchi et al.), and in applications where maintenance of receptor integrity is required, Collagenase Type IV has low tryptic activity compared to other collagenase preparations.
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    Protocols and Documentation

    Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

    Document Type
    Product Name
    Catalog #
    Lot #
    Language
    Catalog #
    07426, 100-0680, 07427
    Lot #
    All
    Language
    English
    Document Type
    Safety Data Sheet
    Catalog #
    07426, 100-0680, 07427
    Lot #
    All
    Language
    English

    Applications

    This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

    Resources and Publications

    Educational Materials (1)

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