切换导航
  • 比较产品
我的购物车

抗小鼠NK1.1（CD161）抗体，克隆PK136

抗小鼠 NK1.1 (CD161) 的 (C3H x BALB/c) F1 杂交单克隆IgG2a抗体
率先评论此产品
添加并比较

产品号 #（选择产品）

产品号 #60103_C

抗小鼠 NK1.1 (CD161) 的 (C3H x BALB/c) F1 杂交单克隆IgG2a抗体

main product photo
总览
实验数据
产品说明书及文档
应用领域
相关材料与文献
相关产品

总览

PK136抗体可特异性识别小鼠NK1.1（CD161）。CD161是一种约80 kDa的同型二聚体2型跨膜糖蛋白和C型凝集素受体，在小鼠NK细胞、NK-T细胞以及特定小鼠品系的稀有T细胞和单核细胞的亚群中表达。NK1.1由Klrb1b和Klrb1c基因编码，这两个基因分别编码CD161b和CD161c多肽。CD161b仅在Swiss NIH和SJL小鼠中表达，CD161c在某些品系如C57BL、FVB/N和NZB中表达，但不在A、AKR、BALB/c、CBA/J、C3H、C57BR、C58、DBA/1、DBA/2、NOD、SJL或129中表达。NK1.1在调节多种生理过程方面发挥功能性作用，包括NK细胞的激活和增殖、诱导干扰素-γ的产生以及释放细胞毒性颗粒。IL-12特异性上调其在细胞表面的表达。对于NK1.1-株的NK细胞检测，推荐使用抗小鼠CD49b抗体，克隆DX5（产品号 #60020）。DX5识别CD49b（整合素α2），这是另一种常用的NK细胞标志物。

亚型
一抗
 
靶抗原
NK1.1 (CD161)
 
别名
CD161b，CD161c，Klrb1b，Klrb1c，Ly-55，Ly-59，NK-1.1，NKRP1，NKRP1a，NKRP1b
 
活性物种
小鼠
 
偶联
Biotin 或 生物素，FITC，PE，未偶联的
 
宿主物种
小鼠
 
细胞类型
NK 细胞
 
种属
小鼠
 
应用
细胞分选，CyTOF，删除，流式细胞术，功能学筛选，免疫细胞化学，免疫荧光，免疫组化，免疫沉淀
 
研究领域
免疫
 
克隆
PK136
 
基因编号
17059
 
同种型
IgG2a，kappa
 

查看更多 显示更少

Data Figures

Data for Unconjugated

Figure 1. Data for Unconjugated

(A) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, followed by a rat anti-mouse IgG2a antibody, PE and Anti-Mouse CD45 Antibody, Clone 30-F11, APC (Catalog #60030AZ). (B) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Mouse IgG2a, kappa Isotype Control Antibody, Clone MOPC173 (Catalog #60071), followed by a rat anti-mouse IgG2a antibody, PE and Anti-Mouse CD45 Antibody, Clone 30-F11, APC.

Data for Alexa Fluor® 488-Conjugated

Figure 2. Data for Alexa Fluor® 488-Conjugated

(A) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, Alexa Fluor® 488 and Anti-Mouse CD45 Antibody, Clone 30-F11, PE (Catalog #60030PE). (B) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Mouse IgG2a, kappa Isotype Control Antibody, Clone MOPC-173, Alexa Fluor® 488 (Catalog #60071AD) and Anti-Mouse CD45 Antibody, Clone 30-F11, PE.

Data for APC-Conjugated

Figure 3. Data for APC-Conjugated

(A) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, APC and Anti-Mouse CD45 Antibody, Clone 30-F11, PE (Catalog #60030PE). (B) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Mouse IgG2a, kappa Isotype Control Antibody, Clone MOPC173, APC (Catalog #60071AZ) and Anti-Mouse CD45 Antibody, Clone 30-F11, PE.

Data for Biotin-Conjugated

Figure 4. Data for Biotin-Conjugated

(A) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, Biotin, followed by streptavidin (SAV) APC and Anti-Mouse CD45 Antibody, Clone 30-F11, FITC (Catalog #60030FI). (B) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Mouse IgG2a, kappa Isotype Control Antibody, Clone MOPC173, Biotin (Catalog #60071BT), followed by SAV APC and Anti-Mouse CD45 Antibody, Clone 30-F11, FITC.

Data for FITC-Conjugated

Figure 5. Data for FITC-Conjugated

(A) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, FITC and Anti-Mouse CD45 Antibody, Clone 30-F11, PE (Catalog #60030PE). (B) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Mouse IgG2a, kappa Isotype Control Antibody, Clone MOPC173, FITC (Catalog #60071FI) and Anti-Mouse CD45 Antibody, Clone 30-F11, PE.

Data for PE-Conjugated

Figure 6. Data for PE-Conjugated

(A) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, PE and Anti-Mouse CD45 Antibody, Clone 30-F11, FITC (Catalog #60030FI). (B) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Mouse IgG2a, kappa Isotype Control Antibody, Clone MOPC-173, PE (Catalog #60071PE) and Anti-Mouse CD45 Antibody, Clone 30-F11, FITC.

Data for PerCP-Cy55-Conjugated

Figure 7. Data for PerCP-Cy55-Conjugated

(A) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, PerCP-Cy5.5 and Anti-Mouse CD45 Antibody, Clone 30-F11, APC (Catalog #60030AZ).

Figure 8. Data for PB-Conjugated

(A) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, Pacific Blue™ and Anti-Mouse CD45 Antibody, Clone 30-F11, FITC (Catalog #60030FI). (B) Flow cytometry analysis of C57BL/6 mouse splenocytes (gated on lymphocytes) labeled with a mouse IgG2a, kappa Pacific Blue™ isotype control antibody and Anti-Mouse CD45 Antibody, Clone 30-F11, FITC.

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, Alexa Fluor® 488
Catalog #
60103AD.1
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, APC
Catalog #
60103AZ.1
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, Biotin
Catalog #
100-0463, 60103BT
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, FITC
Catalog #
60103FI
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, Pacific Blue™
Catalog #
60103PB
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, PerCP-Cy5.5
Catalog #
60103PS, 60103PS.1
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136
Catalog #
100-0459
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, Alexa Fluor® 488
Catalog #
60103AD.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, APC
Catalog #
60103AZ.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, Biotin
Catalog #
100-0463, 60103BT
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, FITC
Catalog #
60103FI
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, Pacific Blue™
Catalog #
60103PB
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136, PerCP-Cy5.5
Catalog #
60103PS, 60103PS.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse NK1.1 (CD161) Antibody, Clone PK136
Catalog #
100-0459
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Research Area
Workflow Stages

Resources and Publications

Educational Materials (3)

Reliable Antibodies for Your Research
Brochure
Reliable Antibodies for Your Research
Tools for Your Immunology Research
Brochure
Tools for Your Immunology Research
Human Immune Cytokines
Wallchart
Human Immune Cytokines

更多信息

更多信息
Species Mouse
Clone PK136
Gene Id 17059
Alternative Names CD161b, CD161c, Klrb1b, Klrb1c, Ly-55, Ly-59, NK-1.1, NKRP1, NKRP1a, NKRP1b
Isotype IgG2a, kappa
Legal Statement: Alexa Fluor and Pacific Blue are trademarks of Life Technologies Corporation. Antibodies conjugated to Alexa Fluor® or Pacific Blue™ are licensed for internal research use only and sale is expressly conditioned on the buyer not using the antibody for manufacturing, performing a service or medical test, or otherwise generating revenue. For use other than research, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
版权 © 2025 STEMCELL Technologies 技术有限公司。保留所有权利。