抗人MUC1 (CD227)抗体,克隆214D4

小鼠单克隆IgG1抗体,抗人MUC1 (CD227)

产品号 #(选择产品)

产品号 #60137_C

小鼠单克隆IgG1抗体,抗人MUC1 (CD227)

总览

214D4抗体识别MUC1(也称为CD227),MUC1是一种在大多数腺体和导管上皮细胞以及多种造血细胞表达的大型细胞表面糖蛋白。MUC1 (CD227)糖蛋白的一个显著特征是其核心蛋白结构中含有可变数目的串联重复序列,并带有多个寡糖侧链。由于 MUC1 的胞外结构的可延伸程度超过大多数细胞表面蛋白,因此它被认为在细胞-细胞以及细胞-基质的黏附中发挥作用。该蛋白在大多数人类腺癌中高度表达,并与预后不良有关。在乳腺中,MUC1位于腔面上皮细胞的顶端质膜上。克隆214D4具有一个特别的使用价值,因为它可富集来源于正常人乳腺组织的腔面上皮前体细胞,而非双能上皮前体细胞。

亚型
一抗
 
靶抗原
MUC1 (CD227)
 
别名
CD227,EMA,Episialin,上皮膜抗原,HMFG抗原,MAM6,黏蛋白1,PEM,多态性上皮黏蛋白
 
活性物种

 
偶联
未偶联的
 
宿主物种
小鼠
 
细胞类型
乳腺细胞
 
种属

 
应用
细胞分选,免疫组化
 
研究领域
上皮细胞研究,干细胞生物学
 
克隆
214D4
 
基因编号
4582
 
同种型
IgG1
 

Data Figures

Flow cytometry analysis of human MCF7 cells labeled with Anti-Human MUC1 (CD227) Antibody, Clone 214D4, followed by a rat anti-mouse IgG1 antibody, FITC (filled histogram) or a mouse IgG1, kappa isotype control antibody, followed by a rat anti-mouse IgG1 antibody, FITC (solid line histogram).

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
60137
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60137
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Resources and Publications

Educational Materials (1)

更多信息

更多信息
Species Human
Clone 214D4
Gene Id 4582
Alternative Names CD227, EMA, Episialin, Epithelial membrane antigen, HMFG antigen, MAM6, Mucin 1, PEM, Polymorphic epithelial mucin
Isotype IgG1
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