切换导航
  • 比较产品
我的购物车

抗人CD5抗体，克隆UCHT2

小鼠抗人、恒河鼠、食蟹虫CD5单克隆IgG1抗体
率先评论此产品
添加并比较

产品号 #（选择产品）

产品号 #60082_C

小鼠抗人、恒河鼠、食蟹虫CD5单克隆IgG1抗体

main product photo
总览
实验数据
产品说明书及文档
应用领域
相关材料与文献
相关产品

概述

UCHT2抗体与CD5反应，CD5是一种~67 kDa的单链I型糖蛋白，是清道夫受体超家族的成员，在胸腺细胞、T细胞、B细胞亚群、外周血树突状细胞和一些白血病和淋巴瘤细胞，包括慢性B淋巴细胞白血病（B- cll）细胞上组成性表达。CD5在胸腺细胞上低水平表达，而在成熟T细胞上高密度表达。假设的配体包括CD5L和CD72。CD5通过其与T细胞受体/CD3复合物和B细胞受体的物理和功能关联，调节T和B细胞受体信号传导、胸腺细胞成熟和T细胞/B细胞相互作用。对CD5敲除小鼠的研究表明，CD5负调控胸腺细胞和成熟T细胞中抗原受体介导的信号传导。UCHT2抗体结合位于CD5细胞外结构域的表位2。

Subtype
Primary Antibodies
 
Target Antigen
CD5
 
Alternative Names
Leu1, Leu-1, Ly-1, Lymphocyte antigen T1, T1, Tp67
 
Reactive Species
Capuchin Monkey, Chimpanzee, Common Marmoset, Cynomolgus, Human, Owl Monkey, Rhesus
 
Conjugation
APC, Biotin, FITC, PE, PerCP-Cyanine5.5, Unconjugated
 
Host Species
Mouse
 
Cell Type
T Cells
 
Species
Human, Non-Human Primate
 
Application
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blotting
 
Area of Interest
Immunology, Stem Cell Biology
 
Clone
UCHT2
 
Gene ID
921
 
Isotype
IgG1, kappa
 

查看更多 显示更少

Data Figures

Data for APC-Conjugated

Figure 1. Data for APC-Conjugated

(A) Flow cytometry analysis of human buffy coat nucleated cells labeled with Anti-Human CD5 Antibody, Clone UCHT2, APC and Anti-Human CD20 Antibody, Clone 2H7, Alexa Fluor® 488 (Catalog #60008AD). (B) Flow cytometry analysis of human buffy coat nucleated cells labeled with a mouse IgG1, kappa APC isotype control antibody and Anti-Human CD20 Antibody, Clone 2H7, Alexa Fluor® 488. (C) Flow cytometry analysis of human buffy coat nucleated cells processed with the EasySep™ HLA Whole Blood CD3 Positive Selection Kit and labeled with Anti-Human CD5 Antibody, Clone UCHT2, APC. Histograms show labeling of buffy coat nucleated cells (Start) and isolated cells (Isolated). Labeling of start cells with a mouse IgG1, kappa APC isotype control antibody is shown (solid line histogram).

Data for Biotin-Conjugated

Figure 2. Data for Biotin-Conjugated

(A) Flow cytometry analysis of human buffy coat nucleated cells labeled with Anti-Human CD5 Antibody, Clone UCHT2, Biotin followed by streptavidin (SAV) APC and Anti-Human CD20 Antibody, Clone 2H7, PE (Catalog #60008PE).
(B) Flow cytometry analysis of human buffy coat nucleated cells labeled with a mouse IgG1, kappa biotin isotype control antibody followed by streptavidin (SAV) APC and Anti-Human CD20 Antibody, Clone 2H7, PE.
(C) Flow cytometry analysis of human buffy coat nucleated cells processed with the EasySep™ HLA CD3 Positive Selection Kit and labeled with Anti-Human CD5 Antibody, Clone UCHT2, Biotin followed by streptavidin (SAV) APC. Histograms show labeling of buffy coat nucleated cells (Start) and isolated cells (Isolated). Labeling of start cells with a mouse IgG1, kappa biotin isotype control antibody followed by SAV APC is shown (open histogram).

Data for FITC-Conjugated

Figure 3. Data for FITC-Conjugated

(A) Flow cytometry analysis of human buffy coat nucleated cells labeled with Anti-Human CD5 Antibody, Clone UCHT2, FITC and Anti-Human CD20 Antibody, Clone 2H7, APC (Catalog #60008AZ). (B) Flow cytometry analysis of human buffy coat nucleated cells labeled with a mouse IgG1, kappa FITC isotype control antibody and Anti-Human CD20 Antibody, Clone 2H7, APC. (C) Flow cytometry analysis of human buffy coat nucleated cells processed with the EasySep™ HLA CD3 Positive Selection Kit and labeled with Anti-Human CD5 Antibody, Clone UCHT2, FITC. Histograms show labeling of buffy coat nucleated cells (Start) and isolated cells (Isolated). Labeling of start cells with a mouse IgG1, kappa FITC isotype control antibody is shown (solid line histogram).

Data for PE-Conjugated

Figure 4. Data for PE-Conjugated

(A) Flow cytometry analysis of human buffy coat nucleated cells labeled with Anti-Human CD5 Antibody, Clone UCHT2, PE and Anti-Human CD20 Antibody, Clone 2H7, APC (Catalog #60008AZ). (B) Flow cytometry analysis of human buffy coat nucleated cells labeled with a mouse IgG1, kappa PE isotype control antibody and Anti-Human CD20 Antibody, Clone 2H7, APC. (C) Flow cytometry analysis of human buffy coat nucleated cells processed with the EasySep™ HLA CD3 Positive Selection Kit and labeled with Anti-Human CD5 Antibody, Clone UCHT2, PE. Histograms show labeling of buffy coat nucleated cells (Start) and isolated cells (Isolated). Labeling of start cells with a mouse IgG1, kappa PE isotype control antibody is shown (solid line histogram).

Data for Unconjugated

Figure 5. Data for Unconjugated

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD5 Antibody, Clone UCHT2, followed by Goat Anti-Mouse IgG (H+L) Antibody, Polyclonal, FITC (Catalog #60138FI) (filled histogram), or a mouse IgG1, kappa isotype control antibody, followed by Goat Anti-Mouse IgG (H+L) Antibody, Polyclonal, FITC (solid line histogram).

Data for PerCP-Cy55-Conjugated

Figure 6. Data for PerCP-Cy55-Conjugated

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD5 Antibody, Clone UCHT2, PerCP-Cy5.5 (filled histogram) or a mouse IgG1, kappa isotype control antibody, PerCP-Cy5.5 (solid line histogram).

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet
Product Name
Anti-Human CD5 Antibody, Clone UCHT2, APC
Catalog #
60082AZ, 60082AZ.1
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Human CD5 Antibody, Clone UCHT2, Biotin
Catalog #
60082BT
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Human CD5 Antibody, Clone UCHT2, FITC
Catalog #
60082FI, 60082FI.1
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Human CD5 Antibody, Clone UCHT2, PE
Catalog #
60082PE, 60082PE.1
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Human CD5 Antibody, Clone UCHT2, PerCP-Cy5.5
Catalog #
60082PS
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Human CD5 Antibody, Clone UCHT2
Catalog #
60082
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human CD5 Antibody, Clone UCHT2, APC
Catalog #
60082AZ, 60082AZ.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human CD5 Antibody, Clone UCHT2, Biotin
Catalog #
60082BT
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human CD5 Antibody, Clone UCHT2, FITC
Catalog #
60082FI, 60082FI.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human CD5 Antibody, Clone UCHT2, PE
Catalog #
60082PE, 60082PE.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human CD5 Antibody, Clone UCHT2, PerCP-Cy5.5
Catalog #
60082PS
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human CD5 Antibody, Clone UCHT2
Catalog #
60082
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Research Area
Workflow Stages

Resources and Publications

Educational Materials (2)

Tools for Your Immunology Research
Brochure
Tools for Your Immunology Research
Human Immune Cytokines
Wallchart
Human Immune Cytokines

更多信息

更多信息
Species Human, Non-Human Primate
Clone UCHT2
Gene Id 921
Alternative Names Leu1, Leu-1, Ly-1, Lymphocyte antigen T1, T1, Tp67
Isotype IgG1, kappa
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
版权 © 2025 STEMCELL Technologies 技术有限公司。保留所有权利。