产品号 #60121_C
Mouse monoclonal IgG1 antibody against human CD34
概述
CD34 is an ~105 - 120 kDa type 1 transmembrane glycoprotein expressed on the surface of most human hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells and some tumor cell lines. The frequency of CD34+ cells is low in bone marrow (1 - 4%), cord blood (~1%), and peripheral blood (< 0.1%). CD34 is used to identify and isolate HSPCs, including those capable of reconstituting hematopoiesis after transplantation. Distinct epitope groups have been assigned to CD34 based on differences in the structure of carbohydrate groups, which affects their sensitivity to enzymatic cleavage. The 8G12 antibody recognizes a class III epitope (resistant to neuraminidase and O-glycoprotease). Clone 8G12 does not recognize rhesus macaque CD34.
Subtype
Primary Antibodies
Target Antigen
CD34
Reactive Species
Human
Conjugation
APC, FITC, PE
Host Species
Mouse
Cell Type
Hematopoietic Stem and Progenitor Cells
Species
Human
Application
Cell Isolation, Flow Cytometry
Area of Interest
Stem Cell Biology
Clone
8G12
Gene ID
947
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Anti-Human CD34 Antibody, Clone 8G12, APC Catalog #
60121AZ Lot #
All Language
English Document Type
Product Information Sheet Product Name
Anti-Human CD34 Antibody, Clone 8G12, PE Catalog #
60121PE Lot #
All Language
English Document Type
Product Information Sheet Product Name
Anti-Human CD34 Antibody, Clone 8G12, FITC Catalog #
60121FI Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Human CD34 Antibody, Clone 8G12, APC Catalog #
60121AZ Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Human CD34 Antibody, Clone 8G12, PE Catalog #
60121PE Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Human CD34 Antibody, Clone 8G12, FITC Catalog #
60121FI Lot #
All Language
English Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Research Area
Workflow Stages
Workflow Stages for Dendritic Cell Research
Workflow Stages for Hematopoietic Stem and Progenitor Cell Research
Workflow Stages for hPSC-Derived Mesoderm Cell Research
Workflow Stages for HLA Analysis
Workflow Stages for Cord Blood Banking
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