抗人 CD298 抗体,克隆 LNH-94

小鼠单克隆IgG1抗体,抗人CD298

产品号 #(选择产品)

产品号 #60159_C

小鼠单克隆IgG1抗体,抗人CD298

总览

LNH-94 抗体与人 CD298(Na+/K+ ATPase 的 β3 亚基)反应。Na+/K+ ATPase 是一种 42 kDa 的 II 型跨膜蛋白,由四个催化 α 亚基和三个较小的糖基化非催化 β 亚基组成。Na+/K+ ATP酶通过耦合ATP水解和Na+和K+的主动转运,在建立电化学梯度和维持正常静息膜电位方面发挥重要作用。据报道,β 亚基可作为伴侣蛋白稳定 α 亚基并阻断 K+。CD298 已被用于识别小鼠异种移植模型中的转移性人癌细胞,并被报道可调节免疫的各个方面,包括 HIV 的产生以及 T 细胞和 B 细胞的活化。CD298 存在于白细胞、血小板和大多数其他组织类型中。

亚型
一抗
 
靶抗原
CD298
 
活性物种

 
偶联
APC,PE
 
宿主物种
小鼠
 
细胞类型
B 细胞,粒细胞及其亚群,淋巴细胞,乳腺细胞,单核细胞,T 细胞
 
种属

 
应用
流式细胞术
 
研究领域
癌症,疾病建模,内皮细胞研究,免疫,移植研究
 
克隆
LNH-94
 
基因编号
483
 

Data Figures

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs; gated on lymphocytes) labeled with Anti-Human CD298 Antibody, Clone LNH-94, PE (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, PE (Catalog #60070PE; solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs; gated on lymphocytes) labeled with Anti-Human CD298 Antibody, Clone LNH-94, APC (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, APC (Catalog # 60070AZ; solid line histogram).

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
60159AZ
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60159AZ
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Resources and Publications

Educational Materials (2)

更多信息

更多信息
Species Human
Clone LNH-94
Gene Id 483
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