产品号 #60146_C
Mouse monoclonal IgG1 antibody against human CD326 (EpCAM)
The 323/A3 antibody reacts with the human epithelial cell adhesion molecule (EpCAM or CD326), an ~40 kDa type I transmembrane glycoprotein which functions as a homophilic and Ca++-independent adhesion molecule. EpCAM has roles in several cellular processes, including signaling, migration, proliferation, and differentiation. It is expressed early during erythrogenesis and has been identified as a stem cell marker. The EpCAM protein is found on the basolateral membrane of most normal epithelial cells and is highly expressed in bone marrow, colon, and lung. EpCAM is not expressed on mesothelial cells or mesotheliomas, and so is widely used as a diagnostic marker to distinguish mesothelioma and carcinoma cells, as well as serving as a target for immunotherapeutic treatment of carcinomas.
Subtype
Primary Antibodies
Target Antigen
CD326 (EpCAM)
Alternative Names
EGP2, EpCAM, Epithelial cell adhesion molecule, ESA, TACSTD1, TROP-1
Reactive Species
Human
Conjugation
Unconjugated
Host Species
Mouse
Cell Type
Mammary Cells
Species
Human
Application
Cell Isolation, Flow Cytometry, Immunocytochemistry, Immunohistochemistry
Area of Interest
Epithelial Cell Biology, Stem Cell Biology
Clone
323/A3
Gene ID
4072
Isotype
IgG1, kappa
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Thank you for your interest in IntestiCult™ Organoid Growth Medium (Human). Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n):
Estimated delivery time for your area
Product sample or exclusive offer
In-lab demonstration
扫描二维码或搜索微信号STEMCELLTech,即可关注我们的微信平台,第一时间接收丰富的技术资源和最新的活动信息。
如您有任何问题,欢迎发消息给STEMCELLTech微信公众平台,或与我们通过电话/邮件联系:400 885 9050 INFO.CN@STEMCELL.COM。