TMRE(高氯酸盐)

一种可透过细胞膜的阳离子荧光染料,用于检测线粒体膜电位

产品号 #(选择产品)

产品号 #100-0992_C

一种可透过细胞膜的阳离子荧光染料,用于检测线粒体膜电位

使用TMRE(高氯酸盐)染色检测线粒体膜电位变化。TMRE 采用快速简便的染色流程,非常适合高通量筛选,并与流式细胞术兼容。

特点:
•激发波长:552nm
•发射波长:574 nm
•保留依赖于线粒体内膜电位
•验证可用于流式细胞术

TMRE 是一种可透过细胞膜的阳离子化合物,可发出红橙色荧光信号。它很容易积聚在具有高膜电位的线粒体中,而去极化的线粒体则无法保留该染料。
TMRE具有足够的保留时间,是细胞分选,进一步纯化和鉴定的最佳选择(Barteneva et al. J Histochem Cytochem, 2014)。TMRE不会抑制线粒体功能,可用于凋亡细胞的发现(Barteneva et al., 2014)。

Data Figures

Figure 1. TMRE (Perchlorate) Is Not Retained in Apoptotic Cells

Flow cytometry analysis of Jurkat cells labeled with TMRE after incubation in the presence or absence of staurosporine, an inducer of apoptosis.

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

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Catalog #
Lot #
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Catalog #
100-0992
Lot #
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Language
English
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Safety Data Sheet
Catalog #
100-0992
Lot #
All
Language
English

Applications

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Molecular Weight 514.95 g/mol
Cas Number 115532-52-0
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