Tacrine (Hydrochloride)

L-type calcium channel inhibitor; Inhibits acetylcholinesterase and butyrylcholinesterase

产品优势

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Tacrine potently inhibits acetylcholinesterase and butyrylcholinesterase (IC50 = 31 and 26.5 nM, respectively; Ahmed et al.). It also inhibits both human and rat histamine-N-methyltransferase in a dose-dependent manner (Taraschenko et al.). Tacrine is used in the treatment of Alzheimer's disease (Ahmed et al.; McKenna et al.; Taraschenko et al.).

DISEASE MODELING
· Inhibits L-type calcium channels and decreases the influx of calcium in mouse neurons (Dolezal et al.).
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Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-0888
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-0888
Lot #
All
Language
English
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Resources and Publications

Educational Materials (1)

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