JCV (VP1)肽库

JC多瘤病毒(VP1)肽库用于免疫细胞激活

产品号 #(选择产品)

产品号 #100-1400_C

JC多瘤病毒(VP1)肽库用于免疫细胞激活

用JCV (VP1)肽库刺激T细胞释放下游细胞因子并上调激活标记物,使抗原特异性T细胞能够被检测或分离用于分析。该肽库是由JC多瘤病毒(JCV)主要衣壳蛋白VP1 (VP1)的86个肽组成的冻干混合物。该肽库由15个氨基酸组成的肽段构成,每条肽之间有11个氨基酸的重叠,覆盖了 VP1 蛋白第 1 至 354 位氨基酸区域。VP1结合宿主细胞糖蛋白和糖脂中的LSTc寡糖,这种相互作用被认为是JCV病毒生长和传染性所必需的(Neu等人)。JCV VP1 (Del Valle等人)和大T抗原(Delbue等人)在JCV相关病理中被检测到,如HIV患者的进行性多灶性脑白质病(PML)。病毒肽库的应用范围很广,包括疫苗开发、免疫学研究和诊断检测方法的开发。

Protocols and Documentation

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Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-1400
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-1400
Lot #
All
Language
English

Applications

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Species Other
Purity Average 70%
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.
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