JCV (LT)肽库

JC多瘤病毒(大T)肽库用于免疫细胞激活

产品号 #(选择产品)

产品号 #100-1399_C

JC多瘤病毒(大T)肽库用于免疫细胞激活

用JCV (LT)肽库刺激T细胞释放下游细胞因子并上调激活标记物,使抗原特异性T细胞能够被检测或分离用于分析。这个肽库是由来自JC多瘤病毒(JCV)大T抗原(LT)的170个肽组成的冻干混合物,该肽库由15个氨基酸组成的肽段构成,每条肽之间有11个氨基酸的重叠,覆盖了 LT 蛋白的第 1 至 688 位氨基酸。LT可在JC潜伏期被检测到(Rossi等),也可在患有JC相关病变(如进行性多灶性白质脑病(PML))的免疫功能低下患者中检测到(Delbue等)。在PML中,LT与激活survivin(一种抗凋亡蛋白)启动子有关(Del Valle等)。病毒肽库的应用范围很广,包括疫苗开发、免疫学研究和诊断检测方法的开发。

Protocols and Documentation

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Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-1399
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-1399
Lot #
All
Language
English

Applications

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Species Other
Purity Average 70%
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.
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