产品号 #78123_C
转化生长因子α
转化生长因子-α (TGF-α)是表皮生长因子(EGF)家族的一员,在正常上皮细胞、单核细胞、巨噬细胞、脑细胞、角质形成细胞和癌细胞中均有表达。TGF-α可与表皮生长因子受体(EGFR)结合,并激活酪氨酸激酶信号通路。在表皮和上皮细胞中,这可促使细胞增殖和分化。TGF-α与TGF-β在结构和基因上均无关联,两种配体通过不同的信号通路起作用。在体外实验终,TGF-α被证明可以刺激细胞的非锚定生长(Singh & Coffey)。
亚型
细胞因子,生长因子
细胞类型
气道细胞,上皮细胞,乳腺细胞,前列腺细胞
种属
人
研究领域
上皮细胞研究
纯度
≥ 95 %
(A) The biological activity of Human Recombinant TGF-alpha was tested by its ability to promote the proliferation of BALB/c 3T3 cells. Cell proliferation was measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum. The EC50 in the above example is less than 0.2 ng/mL. (B) 2 μg of Human Recombinant TGF-alpha was resolved with SDS-PAGE under reducing (+) conditions and visualized by Coomassie Blue staining.
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Thank you for your interest in IntestiCult™ Organoid Growth Medium (Human). Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n):
Estimated delivery time for your area
Product sample or exclusive offer
In-lab demonstration
Species | Human |
---|---|
Purity | ≥ 95% |
培养人神经干细胞和祖细胞的培养基
人神经干细胞和祖细胞分化的培养基
用于建立和维持小鼠肠道类器官的培养基
杜氏磷酸盐缓冲液,不含钙和镁离子
扫描二维码或搜索微信号STEMCELLTech,即可关注我们的微信平台,第一时间接收丰富的技术资源和最新的活动信息。
如您有任何问题,欢迎发消息给STEMCELLTech微信公众平台,或与我们通过电话/邮件联系:400 885 9050 INFO.CN@STEMCELL.COM。