产品号 #100-1294_C
Resistin
Use resistin to modulate various cellular responses, such as promoting neutrophil extracellular trap (NET) formation (Jiang et al.) and regulating anti-inflammatory signaling pathways through toll-like receptor 4 (TLR4) (Jang et al., 2017). A member of the resistin-like molecule (RELM) family, resistin is produced by adipocytes in mice, and has been implicated in insulin resistance, reducing glucose tolerance, and insulin sensitivity in vivo (Li et al.). In humans, resistin is expressed predominantly in leukocytes, modulating inflammation in numerous diseases (Jamaluddin et al.; Jang et al., 2015; Mantula et al.). Studies also show that resistin facilitates vascular endothelial growth factor (VEGF)-A-dependent angiogenesis in human chondrosarcoma cells, highlighting it as a promising target for chondrosarcoma angiogenesis (Chen et al.). For consistency and reproducibility across your applications, resistin from STEMCELL comes lyophilized with ≥ 95% purity, and endotoxin levels are verified to be ≤ 1.0 EU/μg protein.
Subtype
Cytokines
Alternative Names
ADSF, FIZZ3
Species
Human
Area of Interest
Metabolism
Purity
≥ 95%
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
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