产品号 #100-1296_C
骨桥蛋白，His标签
总览
骨桥蛋白（OPN）是 SIBLING 糖蛋白家族的成员之一（Rangaswami等人），作为Th1 型细胞因子，在细胞信号传导、迁移和激活中发挥重要作用（Weber等人，2002）。骨桥蛋白已被证明在体内和体外都能调节炎症反应(Agnholt等；Kiefer等)，并与许多癌症的病理生理有关，包括前列腺癌（Thalmann等）、肺癌（Chambers等）、卵巢癌（Kim等）和乳腺癌（Weber等，2015）。在人类中，骨桥蛋白最初以317个氨基酸组成的蛋白形式分泌，随后在组织特异性条件下经过糖基化、磷酸化及转谷氨酰化等翻译后修饰（Kazanecki 等人；Sodek 等人）。本蛋白产品在多肽链的氨基末端带有His标签。为确保各种应用中的一致性与可重复性，STEMCELL 提供的骨桥蛋白为冻干粉，纯度≥92%，内毒素水平经验证不高于 1.0 EU/μg 蛋白。
亚型
细胞因子
别名
BNSP，BSPI，ETA-1，OPN，SPP1
种属
人
研究领域
代谢
纯度
≥ 92%
Data Figures
Human Recombinant Osteopontin was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining. Human Recombinant Osteopontin has a predicted molecular mass of 20.64 kDa but an apparent molecular mass of 35 kDa due to glycosylation.
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Human Recombinant Osteopontin Catalog #
100-1296 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Human Recombinant Osteopontin Catalog #
100-1296 Lot #
All Language
English Request Pricing
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更多信息
| Species | Human |
|---|---|
| Alternative Names | BNSP, BSPI, ETA-1, OPN, SPP1 |
| Purity | ≥ 92% |
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.
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