产品号 #100-1325_C
Omentin
概述
Use omentin for the maintenance of insulin sensitivity and metabolism; decreasing levels of this adipokine have been associated with obesity, insulin resistance, and diabetes (Tan et al.). Studies have suggested that omentin may have protective effects against atherosclerosis, arterial calcification, and myocardial injury through AMP-activated protein kinase (AMPK) and Akt-dependent mechanisms (Xu et al., Kataoka et al.). Through regulation of Sirt1-dependent p53 deacetylation, omentin can inhibit proliferation and induce apoptosis in hepatocellular carcinoma cells (Zhang and Zhou). Omentin is mainly produced by visceral adipose tissue, but is also expressed in the small intestine, colon, mesothelial cells, vascular cells, and plasma (Watanabe et al). Protein sequence analysis has shown that omentin comprises 313 amino acids, with a secretory signal sequence and fibrinogen-related domain (Yang et al.). For consistency and reproducibility across your applications, Omentin from STEMCELL comes lyophilized with ≥ 90% purity, and is verified by LAL analysis to ensure endotoxin levels are ≤ 5.0 EU/μg protein.
Subtype
Cytokines
Alternative Names
Intelectin-1, ITLN-1
Species
Human
Area of Interest
Metabolism
Purity
≥ 90%
Data Figures
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Human Recombinant Omentin Catalog #
100-1325 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Human Recombinant Omentin Catalog #
100-1325 Lot #
All Language
English Request Pricing
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PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.
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