产品号 #100-1325_C
网膜蛋白
总览
使用Omentin 可用于维持胰岛素敏感性和代谢功能；该脂肪因子水平的降低与肥胖、胰岛素抵抗和糖尿病有关（Tan等）。研究表明，Omentin可能通过AMP激活的蛋白激酶（AMPK）和AKT依赖机制，对动脉粥样硬化、动脉钙化和心肌损伤具有保护作用（Xu et al., Kataoka et al.）。Omentin还能通过调控sirt1依赖性的p53去乙酰化，抑制肝癌细胞增殖，诱导细胞凋亡（Zhang and Zhou）。Omentin主要由内脏脂肪组织产生，但在小肠、结肠、间皮细胞、血管细胞和血浆中也有表达（Watanabe等）。蛋白质序列分析表明，Omentin由313个氨基酸组成，具有分泌信号序列和纤维蛋白原相关结构域（Yang等）。STEMCELL公司提供的Omentin以冻干粉形式供应，纯度≥90%，经过LAL分析验证，确保内毒素水平≤5.0 EU/μg蛋白，从而在各种应用中确保一致性和可重复性。
亚型
细胞因子
别名
Intelectin-1，ITLN-1
种属
人
研究领域
代谢
纯度
≥ 90%
Data Figures
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Human Recombinant Omentin Catalog #
100-1325 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Human Recombinant Omentin Catalog #
100-1325 Lot #
All Language
English Request Pricing
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更多信息
| Species | Human |
|---|---|
| Alternative Names | Intelectin-1, ITLN-1 |
| Purity | ≥ 90% |
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.
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