产品号 #74242_C
抑制自噬作用和液泡H+-ATP酶（V-ATPase）
总览
巴佛洛霉素A1（Bafilomycin A1)是一种大环内酯类抗生素药物和自噬抑制剂。它通过抑制液泡H+- ATP酶 (V-ATPase; Klionsky et al.)来阻止自噬体的酸化。
维持和自我更新
·抑制人间充质干细胞中与自噬相关的蛋白水解降解（Oliver et al.）。
癌症研究
·在低浓度下，它可抑制儿童B细胞急性淋巴细胞白血病 (B-ALL) 细胞的自噬并促进其凋亡（Yuan et al.）。
细胞类型
B 细胞，癌细胞及细胞系，白血病/淋巴瘤细胞，间充质干/祖细胞
种属
人，小鼠，非人灵长类，其它细胞系，大鼠
应用
培养
研究领域
自噬，癌症，免疫，干细胞生物学
CAS 编号
88899-55-2
化学式
C₃₅H₅₈O₉
纯度
≥ 95 %
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Resources and Publications
Educational Materials (3)
更多信息
| Species | Human, Mouse, Non-Human Primate, Other, Rat |
|---|---|
| Cas Number | 88899-55-2 |
| Chemical Formula | C₃₅H₅₈O₉ |
| Purity | ≥ 95% |
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
