抗小鼠CD27抗体,克隆LG.3A10

抗人、小鼠、大鼠CD27的仓鼠(亚美尼亚)单克隆IgG1抗体

产品号 #(选择产品)

产品号 #60160_C

抗人、小鼠、大鼠CD27的仓鼠(亚美尼亚)单克隆IgG1抗体

总览

LG.3A10抗体可特异性识别CD27分子(45-55 kDa),是肿瘤坏死因子受体超家族中的成员。CD27存在于人的外周T细胞、记忆B细胞和NK细胞中,以及小鼠除CD46-CD8-前体细胞外的大多数胸腺细胞中。CD27及其配体CD70参与T细胞生物学的多个过程,包括CD4+和CD8+ T细胞的共刺激和扩增,以及CD8+ 记忆T细胞的分化。CD27与TRAF家族成员相互作用,从而促进细胞增殖并诱导抗凋亡蛋白的表达。此外,CD27在T细胞-B细胞相互作用以及效应T细胞的成熟中也发挥着重要作用。据报道,CD27 还能增强激活后B细胞的扩增及其向浆细胞的分化。

亚型
一抗
 
靶抗原
CD27
 
别名
LPFS2,S152,T14,TNFRSF7,Tp55
 
活性物种
人,小鼠,大鼠
 
偶联
PE,未偶联的
 
宿主物种
Hamster
 
细胞类型
B 细胞,NK 细胞,其它细胞系,T 细胞
 
应用
流式细胞术,功能学筛选,免疫组化,免疫沉淀
 
研究领域
免疫,感染性疾病(传染病)
 
克隆
LG.3A10
 
基因编号
21940/939/500318
 
同种型
IgG1,kappa
 

Data Figures

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD27 Antibody, Clone LG.3A10, followed by a goat anti-hamster (Armenian) IgG antibody, Alexa Fluor® 488 (filled histogram), or an Armenian hamster IgG isotype control antibody, followed by a goat anti-hamster (Armenian) IgG antibody, Alexa Fluor® 488 (solid line histogram).

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD27 Antibody, Clone LG.3A10, PE (filled histogram) or an Armenian hamster IgG isotype control antibody, PE (solid line histogram).

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
60160PE.1
Lot #
All
Language
English
Catalog #
60160
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60160PE.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60160
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Resources and Publications

Educational Materials (2)

更多信息

更多信息
Clone LG.3A10
Gene Id 21940/939/500318
Alternative Names LPFS2, S152, T14, TNFRSF7, Tp55
Isotype IgG1, kappa
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