产品号 #60160_C
抗人、小鼠、大鼠CD27的仓鼠(亚美尼亚)单克隆IgG1抗体
LG.3A10抗体可特异性识别CD27分子(45-55 kDa),是肿瘤坏死因子受体超家族中的成员。CD27存在于人的外周T细胞、记忆B细胞和NK细胞中,以及小鼠除CD46-CD8-前体细胞外的大多数胸腺细胞中。CD27及其配体CD70参与T细胞生物学的多个过程,包括CD4+和CD8+ T细胞的共刺激和扩增,以及CD8+ 记忆T细胞的分化。CD27与TRAF家族成员相互作用,从而促进细胞增殖并诱导抗凋亡蛋白的表达。此外,CD27在T细胞-B细胞相互作用以及效应T细胞的成熟中也发挥着重要作用。据报道,CD27 还能增强激活后B细胞的扩增及其向浆细胞的分化。
亚型
一抗
靶抗原
CD27
别名
LPFS2,S152,T14,TNFRSF7,Tp55
活性物种
人,小鼠,大鼠
偶联
PE,未偶联的
宿主物种
Hamster
细胞类型
B 细胞,NK 细胞,其它细胞系,T 细胞
应用
流式细胞术,功能学筛选,免疫组化,免疫沉淀
研究领域
免疫,感染性疾病(传染病)
克隆
LG.3A10
基因编号
21940/939/500318
同种型
IgG1,kappa
Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD27 Antibody, Clone LG.3A10, followed by a goat anti-hamster (Armenian) IgG antibody, Alexa Fluor® 488 (filled histogram), or an Armenian hamster IgG isotype control antibody, followed by a goat anti-hamster (Armenian) IgG antibody, Alexa Fluor® 488 (solid line histogram).
Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD27 Antibody, Clone LG.3A10, PE (filled histogram) or an Armenian hamster IgG isotype control antibody, PE (solid line histogram).
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Clone | LG.3A10 |
---|---|
Gene Id | 21940/939/500318 |
Alternative Names | LPFS2, S152, T14, TNFRSF7, Tp55 |
Isotype | IgG1, kappa |
免疫磁珠负选未标记的人Naïve B细胞
全血免疫磁珠负选试剂盒
全血免疫磁珠负选试剂盒
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