产品号 #100-1066_C
兔抗人villin 1多克隆抗体
该兔多克隆抗体可识别人源villin 1,这是一种表达在上皮细胞中的钙调节蛋白。Villin 1由六个保守结构域组成,形成villin核心区,另带有一个C端头部结构域,该结构域含有一个F-肌动蛋白(F-actin)结合位点。该多克隆抗体适用于需要检测villin 1的实验应用,如蛋白印迹(Western blot, WB)和免疫组织化学(IHC)检测,并已验证可用于免疫细胞化学(ICC)实验。
Villin 1在微绒毛中肌动蛋白丝的重塑过程中发挥重要作用,参与肌动蛋白的成核、聚合和切割过程。它是肠道上皮细胞生长和发育的关键调节因子,影响细胞形态、生长和凋亡。研究表明,villin 1可能是子宫颈内膜、结肠及肺部某些腺癌的预测因子。同时,villin 1的异常表达也与胆道闭锁和胆汁淤积有关。
亚型
一抗
靶抗原
Villin1
别名
D2S1471,VIL1,VIL
活性物种
人
偶联
未偶联的
宿主物种
兔
细胞类型
肠道细胞
种属
人
应用
免疫细胞化学,免疫荧光,免疫组化,Western印迹
研究领域
类器官
克隆
Not applicable
基因编号
7429
同种型
Not applicable
Figure 1. Anti-Human Villin 1 Antibody, Polyclonal is Suitable for Staining Human Intestinal Organoids
H9 human intestinal organoids were cultured using STEMdiff™ Intestinal Organoid Kit (Catalog # 05140), then fixed and labeled with Anti-Human Villin 1 Antibody, Polyclonal, followed by Goat Anti-Rabbit IgG (H+L) Antibody, Polyclonal, iFluor™ 568 (Catalog #100-1083). Nuclei were counter-stained with DAPI (blue). Inset shows cells labeled with a rabbit IgG isotype control antibody, followed by Goat Anti-Rabbit IgG (H+L) Antibody, Polyclonal, iFluor™ 568 (with DAPI staining).
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
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Species | Human |
---|---|
Clone | Not applicable |
Gene Id | 7429 |
Alternative Names | D2S1471, VIL1, VIL |
Isotype | Not applicable |
DNA标记染料
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