抗人 Villin 1 多克隆抗体

兔抗人villin 1多克隆抗体

产品号 #(选择产品)

产品号 #100-1066_C

兔抗人villin 1多克隆抗体

总览

该兔多克隆抗体可识别人源villin 1,这是一种表达在上皮细胞中的钙调节蛋白。Villin 1由六个保守结构域组成,形成villin核心区,另带有一个C端头部结构域,该结构域含有一个F-肌动蛋白(F-actin)结合位点。该多克隆抗体适用于需要检测villin 1的实验应用,如蛋白印迹(Western blot, WB)和免疫组织化学(IHC)检测,并已验证可用于免疫细胞化学(ICC)实验。

Villin 1在微绒毛中肌动蛋白丝的重塑过程中发挥重要作用,参与肌动蛋白的成核、聚合和切割过程。它是肠道上皮细胞生长和发育的关键调节因子,影响细胞形态、生长和凋亡。研究表明,villin 1可能是子宫颈内膜、结肠及肺部某些腺癌的预测因子。同时,villin 1的异常表达也与胆道闭锁和胆汁淤积有关。

亚型
一抗
 
靶抗原
Villin1
 
别名
D2S1471,VIL1,VIL
 
活性物种

 
偶联
未偶联的
 
宿主物种

 
细胞类型
肠道细胞
 
种属

 
应用
免疫细胞化学,免疫荧光,免疫组化,Western印迹
 
研究领域
类器官
 
克隆
Not applicable
 
基因编号
7429
 
同种型
Not applicable
 

Data Figures

Figure 1. Anti-Human Villin 1 Antibody, Polyclonal is Suitable for Staining Human Intestinal Organoids

H9 human intestinal organoids were cultured using STEMdiff™ Intestinal Organoid Kit (Catalog # 05140), then fixed and labeled with Anti-Human Villin 1 Antibody, Polyclonal, followed by Goat Anti-Rabbit IgG (H+L) Antibody, Polyclonal, iFluor™ 568 (Catalog #100-1083). Nuclei were counter-stained with DAPI (blue). Inset shows cells labeled with a rabbit IgG isotype control antibody, followed by Goat Anti-Rabbit IgG (H+L) Antibody, Polyclonal, iFluor™ 568 (with DAPI staining).

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-1066
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-1066
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

更多信息

更多信息
Species Human
Clone Not applicable
Gene Id 7429
Alternative Names D2S1471, VIL1, VIL
Isotype Not applicable
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
版权 © 2025 STEMCELL Technologies 技术有限公司。保留所有权利。