产品号 #100-1068_C
Rabbit polyclonal antibody against human lysozyme
概述
This rabbit polyclonal antibody reacts with human lysozyme, a secreted protein found in high concentration in various tissues and fluids, such as in liver, articular cartilage, saliva, and tears. Use this polyclonal antibody in applications requiring lysozyme detection, such as immunohistochemistry protocols (IHC-P). It has been verified for use with immunocytochemistry (ICC).
Lysozyme performs bacteriolytic functions, hydrolyzing the β-1,4 glycosidic linkages that are found on the peptidoglycan cell walls of various bacteria. Lysozyme also plays an important role in the modulation of pro-inflammatory immune responses. Particularly, the lysozyme-catalyzed degradation of bacteria results in inflammasome activation and macrophage recruitment through cytosolic receptors, like NOD1 and NOD2. In addition to its importance in driving a pro-inflammatory response, lysozyme also plays a role in limiting inflammation by reducing AGE-induced IL-6 production.
Subtype
Primary Antibodies
Target Antigen
Lysozyme
Alternative Names
1,4-Beta-N-Acetylmuramidase C, LYZF1, LZM
Reactive Species
Human
Conjugation
Unconjugated
Host Species
Rabbit
Cell Type
Intestinal Cells
Species
Human
Application
Immunocytochemistry, Immunofluorescence, Immunohistochemistry
Area of Interest
Organoids
Clone
Not applicable
Gene ID
4069
Isotype
Not applicable
Data Figures
Figure 1. Anti-Human Lysozyme Antibody, Polyclonal is Suitable for Staining Primary Differentiated Intestinal Organoid Sections
Primary differentiated intestinal organoid sections from B10 ALI colon lines were deparaffinized and rehydrated with water. The sections went through an antigen retrieval step, were blocked, and then labeled with Anti-Human Lysozyme Antibody, Polyclonal, followed by Goat Anti-Rabbit IgG (H+L) Antibody, Polyclonal, iFluor™ 488 (Catalog #100-1082). Nuclei were counter-stained with DAPI (blue). Inset shows cells labeled with a rabbit IgG isotype control antibody, followed by Goat Anti-Rabbit IgG (H+L) Antibody, Polyclonal, iFluor™ 488 (with DAPI staining).
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Anti-Human Lysozyme Antibody, Polyclonal Catalog #
100-1068 Lot #
All Language
English Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Research Area
Workflow Stages
Workflow Stages for Intestinal Epithelial Cell Research
Resources and Publications
Educational Materials (4)
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