产品号 #100-1067_C
Rabbit polyclonal antibody against human, mouse, rat chromogranin A
概述
This rabbit polyclonal antibody reacts with human, mouse, and rat chromogranin A, a secretory protein found in the cytoplasmic vesicles of neurons and endocrine cells. Use this polyclonal antibody in applications requiring detection of chromogranin A, such as western blotting (WB) assays and immunohistochemistry protocols (IHC-P). It has been verified for use with immunocytochemistry (ICC).
Proteolytic fragments of chromogranin A form functional peptides that help to maintain homeostasis through autocrine and paracrine processes. Chromogranin A and its derivatives play key roles in the inhibition of insulin and leptin secretion in the pancreas and adipocytes, respectively. In addition to its endocrine functions, chromogranin A modulates cardiovascular functions by inhibiting arterial vasoconstriction. Other post-translational derivatives of chromogranin A participate in inflammatory responses and display some potent antimicrobial activity against bacteria and fungi. Elevated measurements of plasma chromogranin A also serve as a biomarker for the diagnosis of neuroendocrine tumors.
Subtype
Primary Antibodies
Target Antigen
Chromogranin A
Alternative Names
CGA, CHGA, Chromogranin A, Parathyroid Secretory Protein 1, SP-I
Reactive Species
Human
Conjugation
Unconjugated
Host Species
Rabbit
Cell Type
Intestinal Cells
Species
Human, Mouse, Rat
Application
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blotting
Area of Interest
Organoids
Clone
Not applicable
Gene ID
1113
Isotype
Not applicable
Data Figures
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Resources and Publications
Educational Materials (4)
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
