抗人CD25抗体,克隆BC96

抗人、恒河猴、食蟹猴CD25的小鼠单克隆IgG1抗体

产品号 #(选择产品)

产品号 #60158_C

抗人、恒河猴、食蟹猴CD25的小鼠单克隆IgG1抗体

总览

BC96抗体可特异性识别人CD25(一种55 kDa的I型跨膜糖蛋白)。CD25参与淋巴细胞的激活和扩增过程,可用于鉴定HIV和HTLV等病毒感染中的T细胞亚群。CD25存在于激活的T细胞和B细胞、单核细胞、巨噬细胞以及调节性T细胞中。CD25、CD4 和 FOXP3的表达被认为是调节性T细胞的表型特征。CD25对其IL-2配体的亲和力较低,但可与 IL-2 受体β(CD122)和常见的γ(CD132)链结合,形成高亲和力的IL-2受体。

亚型
一抗
 
靶抗原
CD25
 
别名
IL‑2 受体 α 链,IL-2Ra,IL2Ra,Tac,p55
 
活性物种
Baboon,Chimpanzee,Cynomolgus,人,Macaque,Rhesus
 
偶联
Alexa Fluor 488,APC,Biotin 或 生物素,FITC,PE,未偶联的
 
宿主物种
小鼠
 
细胞类型
B 细胞,T 细胞,T 细胞,调节性细胞
 
应用
流式细胞术
 
研究领域
癌症,免疫,移植研究,细胞治疗开发
 
克隆
BC96
 
基因编号
3559
 
同种型
IgG1,kappa
 

Data Figures

Flow cytometry analysis of PHA-L-activated human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD25 Antibody, Clone BC96, followed by a rat anti-mouse IgG1 antibody, FITC (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21 (Catalog #60070), followed by a rat anti-mouse IgG1 antibody, FITC (solid line histogram).

Flow cytometry analysis of PHA-L-activated human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD25 Antibody, Clone BC96, FITC (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, FITC (Catalog #60070FI; solid line histogram).

Flow cytometry analysis of PHA-L-activated human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD25 Antibody, Clone BC96, PE (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, PE (Catalog #60070PE; solid line histogram).

Flow cytometry analysis of PHA-L-activated human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD25 Antibody, Clone BC96, APC (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, APC (Catalog #60070AZ; solid line histogram).

Flow cytometry analysis of PHA-L-activated human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD25 Antibody, Clone BC96, Alexa Fluor® 488 (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, Alexa Fluor® 488 (Catalog #60070AD; solid line histogram).

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
60158AZ.1, 60158AZ
Lot #
All
Language
English
Catalog #
60158AD.1, 60158AD
Lot #
All
Language
English
Catalog #
60158BT
Lot #
All
Language
English
Catalog #
60158PE, 60158PE.1
Lot #
All
Language
English
Catalog #
60158FI.1, 60158FI
Lot #
All
Language
English
Catalog #
60158
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60158AZ.1, 60158AZ
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60158AD.1, 60158AD
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60158BT
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60158PE, 60158PE.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60158FI.1, 60158FI
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60158
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Resources and Publications

Educational Materials (2)

更多信息

更多信息
Clone BC96
Gene Id 3559
Alternative Names IL-2 Receptor alpha chain, IL-2Ra, IL2Ra, Tac, p55
Isotype IgG1, kappa
Legal Statement: Alexa Fluor is a registered trademark of Life Technologies Corporation. Antibodies conjugated to Alexa Fluor® are licensed for internal research use only and sale is expressly conditioned on the buyer not using the antibody for manufacturing, performing a service or medical test, or otherwise generating revenue. For use other than research, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
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