抗β-微管蛋白III抗体,克隆TUJ1

抗人、小鼠、大鼠β - 球蛋白III的小鼠单克隆IgG2a抗体

产品号 #(选择产品)

产品号 #60052_C

抗人、小鼠、大鼠β - 球蛋白III的小鼠单克隆IgG2a抗体

总览

TUJ1抗体可与β-微管蛋白 III (beta-tubulin III) 发生反应,β-微管蛋白 III 是一种分子量约为 50 - 55 kDa 的结构蛋白,是微管蛋白的组成部分。微管蛋白是细胞骨架内微管的主要成分,由 α 和 β 微管蛋白亚基的异二聚体组装而成。β-微管蛋白 III 亚型,也称为神经元特异性 III 类 β-微管蛋白,主要在神经元中表达,并被广泛用作区分神经元与其他细胞类型的标志物。β-微管蛋白 III 参与神经元胞体和轴突中微管的形成,该功能涉及GTP结合,并在轴突运输、神经元细胞扩增和分化中发挥作用。它在多种癌症中高表达,是多种肿瘤的预测和预后标志物,例如,它存在于肿瘤细胞中,但在正常的神经胶质细胞中不存在。 TUJ1 抗体预计可识别 β-微管蛋白 III 的所有哺乳动物同源物,据报道表位已定位至该蛋白质的 C 端15个氨基酸。

亚型
一抗
 
靶抗原
Beta-Tubulin III
 
别名
CDCBM,CDCBM1,先天性眼肌麻痹综合征3型,先天性眼肌麻痹综合征3A型,III类β-微管蛋白,FEOM3,TUBB4,β-微管蛋白3链,β-微管蛋白III,β-微管蛋白4链
 
活性物种
人,小鼠,其它细胞系,大鼠
 
偶联
未偶联的
 
宿主物种
小鼠
 
细胞类型
神经细胞,PSC衍生,神经元
 
种属
人,小鼠,大鼠
 
应用
流式细胞术,免疫细胞化学,免疫荧光,免疫组化,免疫沉淀,Western印迹
 
研究领域
神经科学,干细胞生物学
 
克隆
TUJ1
 
基因编号
10381
 
同种型
IgG2a,kappa
 

Data Figures

E18 cortical rat neurons were cultured using NeuroCult™ SM1 Neuronal Culture Kit on poly-L-ornithine and laminin-coated glass coverslips, then fixed and labeled with Anti-Beta-Tubulin III Antibody, Clone TUJ1, followed by donkey anti-mouse IgG, Alexa Fluor® 488, and counterstained with DAPI.

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
60052
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60052
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

更多信息

更多信息
Species Human, Mouse, Rat
Clone TUJ1
Gene Id 10381
Alternative Names CDCBM, CDCBM1, CFEOM3, CFEOM3A, Class III beta-tubulin, FEOM3, TUBB4, Tubulin beta-3 chain, Tubulin beta-III, Tubulin beta-4 chain
Isotype IgG2a, kappa
Legal Statement: Alexa Fluor is a registered trademark of Life Technologies Corporation. Antibodies conjugated to Alexa Fluor® are licensed for internal research use only and sale is expressly conditioned on the buyer not using the antibody for manufacturing, performing a service or medical test, or otherwise generating revenue. For use other than research, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
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