产品号 #100-1173_C
B细胞淋巴瘤2家族抑制剂
总览
ABT-263 是一种化疗药物，也是 B 细胞淋巴瘤 2 (Bcl-2)、超大 B 细胞淋巴瘤 (Bcl-xL) 和 Bcl-2 样蛋白 2 (Bcl-W) 的抑制剂（Ki =
ABT-263 已被用于：
免疫学
·降低巨噬细胞中线粒体抗病毒信号蛋白（MAVS）的表达（Kim et al.）
·通过激活 caspase 9 介导的线粒体凋亡途径诱导甲型流感病毒感染细胞凋亡（Kakkolaet al.）
癌症研究
·抑制小细胞肺癌异种移植模型中的肿瘤生长（Aguilaret al.）
·在体外作为选择性抗衰老药物，在化疗或放疗诱导衰老的肿瘤细胞凋亡后，诱导其凋亡（Saleh et al.）
·促进衰老小鼠Lewis肺癌（LLC）细胞的凋亡（Salehet al.）
·体外诱导人食管癌细胞（EC109、HKESC-2和CaES-17） 的G1/G0期阻滞、细胞凋亡和自噬（Lin et al.）
细胞类型
B 细胞
研究领域
癌症，免疫
CAS 编号
923564-51-6
化学式
C47H55ClF3N5O6S3
分子量
974.6 克/摩尔
纯度
≥98%
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
ABT-263 Catalog #
100-1173 Lot #
All Language
English Resources and Publications
Educational Materials (3)
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更多信息
| Molecular Weight | 974.6 g/mol |
|---|---|
| Cas Number | 923564-51-6 |
| Chemical Formula | C47H55ClF3N5O6S3 |
| Purity | ≥ 98% |
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