产品号 #100-1631_C
Hamster (Syrian) monoclonal antibody against mouse KLRG1
概述
This monoclonal antibody (clone 2F1) reacts with the mouse killer cell lectin-like receptor G1 (KLRG1), a 30 - 38 kDa homodimer receptor and a member of the lectin-like type 2 transmembrane receptor family of proteins. This receptor is expressed by activated, mature natural killer (NK) cells and by effector and memory T cells. KLRG1 expression has been associated with reduced proliferative capacity of activated T lymphocytes or reduced effector functions of activated NK cells. It has also been noted that cell surface expression of KLRG1 is upregulated by expression of the major histocompatibility (MHC) class I molecules, and this can be mediated by interactions with class I-specific Ly49 inhibitory receptors. The expression of mouse KLRG1, using 2F1 antibody clone, has not been detected on the surface of mouse mast cell lines, bone marrow-derived mast cells, or peritoneal mast cells. Use this recombinant monoclonal antibody in applications requiring detection of KLRG1, such as flow cytometry (FC).
Subtype
Primary Antibodies
Target Antigen
KLRG1
Alternative Names
CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
Reactive Species
Mouse
Conjugation
APC, PE
Host Species
Hamster
Cell Type
NK Cells, T Cells, CD8+
Species
Mouse
Application
Flow Cytometry
Area of Interest
Immunology
Clone
2F1
Gene ID
50928
Isotype
Syrian hamster IgG
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Anti-Mouse KLRG1 Antibody, Clone 2F1, APC Catalog #
100-1632 Lot #
All Language
English Document Type
Product Information Sheet Product Name
Anti-Mouse KLRG1 Antibody, Clone 2F1, PE Catalog #
100-1631 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Mouse KLRG1 Antibody, Clone 2F1, APC Catalog #
100-1632 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Mouse KLRG1 Antibody, Clone 2F1, PE Catalog #
100-1631 Lot #
All Language
English Resources and Publications
Educational Materials (2)
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