产品号 #60119_C
Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD34
概述
CD34 is an ~105 - 120 kDa type 1 transmembrane glycoprotein expressed on the surface of most human hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells and some tumor cell lines. The frequency of CD34+ cells is low in bone marrow (1 - 4%), cord blood (~1%), and peripheral blood (< 0.1%). CD34 is used to identify and isolate HSPCs, including those capable of reconstituting hematopoiesis after transplantation. Distinct epitope groups have been assigned to CD34 based on differences in the structure of carbohydrate groups, which affects their sensitivity to enzymatic cleavage. The 563 antibody recognizes a class III epitope (resistant to neuraminidase and O-glycoprotease). Clone 563 also cross-reacts with CD34+ cells of rhesus, cynomolgus, and pigtailed macaques, but not baboons.
Subtype
Primary Antibodies
Target Antigen
CD34
Reactive Species
Cynomolgus, Human, Rhesus
Conjugation
PE
Host Species
Mouse
Cell Type
Hematopoietic Stem and Progenitor Cells
Species
Human, Non-Human Primate
Application
Cell Culture, Flow Cytometry
Area of Interest
Stem Cell Biology
Clone
563
Gene ID
947
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Anti-Human CD34 Antibody, Clone 563, PE Catalog #
60119PE Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Anti-Human CD34 Antibody, Clone 563, PE Catalog #
60119PE Lot #
All Language
English 
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