L755507 is a potent and selective β-3 adrenergic receptor agonist that demonstrates > 440-fold selectivity over β-1 and β-2 binding (EC50 = 0.43, 580, and > 10,000 nM for activation of cloned human β-3-, β-2-, and β-1-adrenoreceptors, respectively; Parmee et al.).
DIFFERENTIATION
· Stimulates lipolysis in human white adipose tissue (Fisher et al.).
GENE EDITING
· Improves the efficiency of homology-directed repair in human induced-pluripotent stem cells following CRISPR editing (Yu et al.).
METABOLISM
· Increases metabolism in rhesus monkeys (Fisher et al.).
DIFFERENTIATION
· Stimulates lipolysis in human white adipose tissue (Fisher et al.).
GENE EDITING
· Improves the efficiency of homology-directed repair in human induced-pluripotent stem cells following CRISPR editing (Yu et al.).
METABOLISM
· Increases metabolism in rhesus monkeys (Fisher et al.).
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Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet
Product Name
L755507
Catalog #
73994, 73992
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
L755507
Catalog #
73994, 73992
Lot #
All
Language
English
Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Research Area
Workflow Stages
Workflow Stages for Human Pluripotent Stem Cell Research
Resources and Publications
Educational Materials (3)
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