Human Platelet Lysate, Pathogen-Reduced, GMP-Compliant
Growth factor-rich supplement for the expansion of cells in vitro
Start experiments confidently with a reliable supply of ethically sourced, GMP-compliant, fibrinogen-depleted, and pathogen-reduced human platelet lysate (hPL) for the expansion of cells in vitro. An alternative to fetal bovine serum (FBS), this growth factor-rich cell culture supplement is derived from healthy donor human platelets, and multiple donor units are pooled during manufacturing to minimize lot-to-lot variability. Heparin is not added during the manufacturing process and is not required for use of this product. An electron beam (e-beam) irradiation step is included in the manufacturing process for pathogen reduction.
hPL is sourced from U.S. Food and Drug Administration (FDA)-registered, AABB-certified blood banks in the United States.
Consent is obtained from volunteers participating in a donor collection program that is reviewed and/or approved by either an Institutional Review Board (IRB), the U.S. FDA, U.S. Department of Health and Human Services, and/or an equivalent regulatory authority.
Certain products are only available in select territories. Please contact your sales representative or Product & Scientific Support at techsupport@stemcell.com for further information.
Browse Frequently Asked Questions (FAQs) on Primary Cells.
hPL is sourced from U.S. Food and Drug Administration (FDA)-registered, AABB-certified blood banks in the United States.
Consent is obtained from volunteers participating in a donor collection program that is reviewed and/or approved by either an Institutional Review Board (IRB), the U.S. FDA, U.S. Department of Health and Human Services, and/or an equivalent regulatory authority.
Certain products are only available in select territories. Please contact your sales representative or Product & Scientific Support at techsupport@stemcell.com for further information.
Browse Frequently Asked Questions (FAQs) on Primary Cells.
Data Figures
Table 1. Properties of Human Platelet Lysate Cell Culture Supplements for Ex Vivo Cell Expansion
The human platelet lysate (hPL) product recommended for the expansion of cells ex vivo varies depending on the starting cell type, intended application, and experimental compliance required. (1) Fibrinogen has not been depleted, therefore addition of an anticoagulant (e.g. Heparin Solution; Catalog #07980) is required to inhibit coagulation. (2) Fibrinogen has been depleted during manufacturing. Pharmaceutical-grade heparin derived from porcine intestine is used in the manufacturing process and the concentration of heparin in final product is ≤ 2 IU/mL. (3) Fibrinogen has been depleted during manufacturing; heparin is not added during the manufacturing process and addition of anticoagulants is not required for use of this product.
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
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Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Research Area
Workflow Stages
Workflow Stages for Mesenchymal Stem and Progenitor Cell Research
Workflow Stages for Mesenchymal Stromal Cell Therapy Development
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