Anti-Mouse KLRG1 Antibody, Clone 2F1

Hamster (Syrian) monoclonal antibody against mouse KLRG1

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This monoclonal antibody (clone 2F1) reacts with the mouse killer cell lectin-like receptor G1 (KLRG1), a 30 - 38 kDa homodimer receptor and a member of the lectin-like type 2 transmembrane receptor family of proteins. This receptor is expressed by activated, mature natural killer (NK) cells and by effector and memory T cells. KLRG1 expression has been associated with reduced proliferative capacity of activated T lymphocytes or reduced effector functions of activated NK cells. It has also been noted that cell surface expression of KLRG1 is upregulated by expression of the major histocompatibility (MHC) class I molecules, and this can be mediated by interactions with class I-specific Ly49 inhibitory receptors. The expression of mouse KLRG1, using 2F1 antibody clone, has not been detected on the surface of mouse mast cell lines, bone marrow-derived mast cells, or peritoneal mast cells. Use this recombinant monoclonal antibody in applications requiring detection of KLRG1, such as flow cytometry (FC).
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Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-1632
Lot #
All
Language
English
Catalog #
100-1631
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-1632
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-1631
Lot #
All
Language
English
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Resources and Publications

Educational Materials (2)

PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.
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